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12 votes
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Can neuron change from excitatory to inhibitory (and vice versa) over time?

As far as I know, it is not possible for a neuron to change which type of neurotransmitter it releases. However, it is the case that the neurotransmitter GABA changes from excitatory to inhibitory ...
honi's user avatar
  • 1,875
11 votes
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Is back-prop biologically plausible?

Biological Plausibility of Back-Prop No, the algorithm of back-prop (BP) isn't biologically plausible. However, there are other means which involve propagating the error through multiple layers of ...
Seanny123's user avatar
  • 8,853
8 votes

Are there neural loops within a column or an area of the cortex?

I've read evidence for single-neuron, two-neuron, and larger loops/cycles throughout the cortex, including intralaminar, interlaminar, and interareal neural loops. But it would take me far too long to ...
John Pick's user avatar
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8 votes
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What role do circular network structures play in neural networks?

In contrast to artificial neural networks, which are almost all feed-forward architectures, networks in biological brains are highly recurrent. In the networks of cortex, the majority of synaptic ...
Dylan Richard Muir's user avatar
8 votes
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What is the capacity of the human brain?

Paul Reber, professor of psychology at Northwestern University, stated that The human brain consists of about one billion neurons. Each neuron forms about 1,000 connections to other neurons, ...
Chris Rogers's user avatar
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7 votes

Are thoughts transferred along with a brain during a brain transplantation?

Short answer Human brain transplants have never been performed, so any answers to what will happen are mere speculations. Background Whole-head transplants have been performed on animals, the first ...
AliceD's user avatar
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6 votes
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What is the role of (why )universal gas constant in Nernst equation?

As in the ideal gas law, the universal gas constant allows for calculation of amount of energy associated with a certain group of molecules (see https://en.wikipedia.org/wiki/Gas_constant). As the ...
honi's user avatar
  • 1,875
6 votes
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What are the advantages of 2AFC in a psychophysical discrimination task?

What makes a task a two alternative forced choice task? I am beginning my answer with this question because there is a general misconception about what 2AFC really means. Many people believe that ...
kindredChords's user avatar
6 votes

Delay time of Transmitting the information from one neuron to another in brain

You mentioned the neurotransmitters released at the synaptic cleft, but seem to be interested in the complete picture. An action potential is actually very slow to propagate down an axon with a ...
aiwyn's user avatar
  • 503
5 votes

What leaps in technology would be needed to scan the total state of the human brain?

Your question can be reduced to "What level of detail do we need to know about a brain to be able to simulate it?" The answer to this question is we have no idea. The Blue Brain project has bet on ...
Seanny123's user avatar
  • 8,853
5 votes

Can "fire together, wire together" be undone?

The phrase "fire together, wire together" comes from an explanation of Hebbian Learning and refers to the adaptation of synapses as a response to the firing of already connected neurons. This is one ...
Seanny123's user avatar
  • 8,853
5 votes

Spike Timing Dependent Plasticity interpretation

The best explanation for STDP that I've ever seen is Nicky Case's Neurotic Neurons. In this Explorable Explanation, I think you'll find that your misunderstanding lies in the fact that both the pre-...
Seanny123's user avatar
  • 8,853
5 votes
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"Nested Neurons": Are they biologically plausible?

Disregarding the feasibility of neurons within neurons in silico, the answer to Is there any evidence for neurons existing within other neurons in humans or other organisms? from a practical, ...
AliceD's user avatar
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5 votes

What does it mean when we say that "a neuron connects to a certain cortical layer"?

Short answer In complicated matters like neural connections in a layered cortex, it is all about semantics. One should carefully place statements in their context and deduce their meaning. ...
AliceD's user avatar
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5 votes
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Can information be lost while traveling through neurotransmitters?

Synapse Information Processing In the Neural Engineering Framework (NEF), synapses are: Leveraged to provide filtering of spikes at different time scales. This allows for managing heterogeneity in ...
Seanny123's user avatar
  • 8,853
5 votes

Brain and General Sections

It depends on the type of addictive substances (i.e., opioid, amphetamine, LSD, etc). Different types bind to different sets of receptors of neurotransmitters (i.e., dopamine, serotonin, GABA, etc.) ...
user287279's user avatar
  • 1,835
5 votes

Cerebellum question

I don't have a clear and definitive answer to give to you but first you should have a look about brain development (from:https://www.apa.org/education/k12/brain-function): And to the function ...
Dadep's user avatar
  • 213
5 votes

Cerebellum question

Hagfish, the most primitive vertebrates, do not appear to have a cerebellum, or if they do have one it is very primitive. Hagfish have most of the other structures found in vertebrate brains (...
Angela Pretorius's user avatar
5 votes
Accepted

Does monism imply that computers can have consciousness?

Note: While "The Basic Theory of the Mind" may potentially be well researched and possibly accurate, it is (as far as I know) a self-published discourse by a non-researcher, that is not peer-reviewed. ...
Arnon Weinberg's user avatar
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5 votes

Is there any justification for viewing neurons as self-interested agents?

The answer to "is there any justification" is pretty much always "yes", but that can be a quite uninteresting "yes" if those justifications are poor. People justify bad ...
Bryan Krause's user avatar
  • 7,551
4 votes

How do the motor system and Central Pattern Generators interact?

Descending inputs onto the central pattern generating circuit provide stimulus in the form of neuromodulatory chemicals and synaptic currents (Marder 2012). The leech heartbeat pacemaker and the ...
Alec Hoyland's user avatar
4 votes

Are there neural loops within a column or an area of the cortex?

Yes, absolutely there are loops, and they can occur on a very small spatial scale. Do we have a proof of local loops in the cortex? Here are a few papers that describe experimental quantification of ...
Dylan Richard Muir's user avatar
4 votes
Accepted

Biological plausibility of RBMs

First, I want to clarify a few things. Deep Learning simply refers to any learning on a deep (more than one hidden layer) neural network, where the learning happens (i.e. parameters are adjusted) at ...
hunse's user avatar
  • 156
4 votes
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Is neurogenesis driven by prediction error?

This question is very difficult to provide a satisfactory answer to because the technical neuroscience definition of prediction error is murky and since your question brings up machine learning then ...
aiwyn's user avatar
  • 503
4 votes
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The role of high-performance in neuropsychology

The short answer to your question is that, yes, you are correct. "Cognitive high performance" is a much smaller part of classic neuropsychology than the study of brain damage. There are studies of the ...
splint's user avatar
  • 1,113
4 votes

What are some credible conferences and journals in computational neuroscience?

Adding to what was already mentioned, there are several "Frontiers" journals: Frontiers in Neuroscience Frontiers in Neural Circuits Frontiers in Computational Neuroscience Frontiers in Synaptic ...
awakenting's user avatar
4 votes
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Learning In Retina

It is not immutable. There are many studies on retinal plasticity, for example using laser coagulation and showing that after selective lesions new connections can be formed even in the adult retina, ...
matteo's user avatar
  • 156
4 votes
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What is the consequences to be a person who works in theory of science?

Quoting from "Cognitive Reflection and Decision Making" Many researchers have emphasized the distinction between two types of cognitive processes: those executed quickly with little conscious ...
got trolled too much this week's user avatar
4 votes
Accepted

How long can neuron adaptation last?

An Adaptive LIF is just one approximation of a biological learning rule. It is not a model for how biology actually works. The most-studied biological learning rule is long-term potentiation in the ...
Bryan Krause's user avatar
  • 7,551
4 votes
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What extent is non linear dynamics and chaos helpful to study brain function?

Since this an active and relatively new area of research, nobody can tell you for certain where it will lead. Whether it will "dead end" is perhaps the wrong way to think about it too. All lines of ...
PhiloT's user avatar
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