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Questions tagged [theoretical-neuroscience]

For questions about mathematical and computational neuroscience.

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0answers
27 views

How does a brain learn strategies?

Imagine the simple task of finding words in a wordsearch. Initially the default strategy might be just to let your eyes wander around to see if you spot any words. Strategy 2 might be to search for ...
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17 views

When did dyslexia emerge as a neurological difference?

I am wondering if dyslexics have one common ancestor? And when did dyslexia emerge as a neurological difference?
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1answer
54 views

Is there any Sleep limit for a human body?

Can we sleep throughout our whole life if we are supplied the necessary things like food,water etc.
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1answer
29 views

Methods to find patterns or correlations in MEA spike trains

I am looking for methods currently used to analyze micro-electrode arrays spike trains and figure out patterns, as repeated sequences of activation or spacial correlations. I know about ISI ...
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1answer
100 views

Biologically plausible models for causal inference in the human brain

Introduction: In ‘Is coding a relevant metaphor for the brain?’(2018) Romain Brette argues that the causal structure of neural codes (linear, atemporal) is incongruent with the causal structure of ...
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1answer
65 views

Constraints on dataset size for AI-assisted connectome reconstruction

From an exchange with Dr. Seung, an expert on connectomics, I learned that one of his former PhD students Viren Jain is leading the Connectomic effort at Google using supervised learning methods. Now, ...
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2answers
164 views

ML/Neuroscience: TensorFlow vs PyTorch vs Keras for bulding NN models of the nervous system?

I would be very grateful to people with experience in using neural network models in neuroscience for advice! What approach would you recommend for building neural networks? I am choosing between ...
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2answers
155 views

Good neuroscience research blogs

In the field of AI research there are really good research blogs that regularly analyse methods and review papers. Examples that come to mind are: BAIR blog: The Berkeley AI Research blog Distill: an ...
2
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1answer
95 views

Understanding the 'Wiring Catastrophe'

Introduction: In 'Wiring optimization in the brain'(2000), Dmitri Chklovskii and Charles Stevens analyse the dependence of the complexity of cortical circuits on the number of synapses per neuron ...
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1answer
64 views

Modelling the Human Brain as a directed graph

A mathematician on the MathOverflow, Hans-Peter Stricker, recently(2016) considered the possibility that human brains may be modelled as directed graphs with neurons as nodes and synapses as edges. I ...
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59 views

What's the pathfinding algorithm the human brain uses?

I was trying to build a software simulation of people using different pathways in a city to get from point A to point B. I do know the Dijkstra's algorithm and the A* algorithm, but what they do is to ...
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1answer
58 views

How does a brain without sensory inputs function?

If for some reasons a brain would be deprived off all inputs, it (he/she) would still have memories to process and all thoughts would be based on past experiences. But in case a person was born ...
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1answer
127 views

What sources of randomness does the brain use for sampling?

As an applied mathematician, I have a growing interest in the mechanisms for uncertainty representation and computation in the human brain. In fact, I recently compiled a list of papers on this ...
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64 views

What is the state of the art on the wiring optimisation problem?

One of the earliest neuroscientists, Santiago Ramón y Cajal, postulated that brains are arranged to minimise wire length [1]. In [1] Dmitri Chklovskii and Charles Stevens formulate this problem as ...
2
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1answer
35 views

Homogeneous Poisson Process of spike train

In Theoretical Neuroscience by Dayan and Abbott page 25, the probability $P[t_1, t_2, ..., t_n]$ that a sequence of n spikes occurs with spike $i$ falling between times $t_i$ and $t_i+\Delta t$ ...
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2answers
58 views

Simulating Hudgkin Huxley neural network

I'm starting work on a computational neuroscience project where I want to create my own model of a spiking Hodgkin-Huxley neuron and connect many instances (about 400) of this model through synapses. ...
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30 views

Timeframe in which thoughts are concieved [closed]

Are thoughts concieved in realtime or are they preprocessed chains ready to be thought or both (depending on the prospective) or am I asking a too generalized question to have any sense ?
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2answers
73 views

Cerebellum question

Sorry if this sounds at all like pretentious armchair theorizing(it basically is), but I have a question which I can't really figure out how to search. So, given the resemblance of the cerebellum to ...
3
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1answer
105 views

Integrated Information Theory - If correct could humans create artificial consciousness?

First off please keep in mind I am self-learning and am learning about this for fun, I have no end goal. I'm trying to make predictions about what I am learning implies or means, so I can ask better ...
2
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1answer
42 views

Is there any evidence for or against the existence of neurons that encode surface slant in vision?

In the way orientation columns display selectivity for various edge orientations projected on the retina which is then repeated at various angles in a localised region of the cortex. I am wondering ...
3
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1answer
68 views

How to define “current” in artificial neural network?

How do neuroscientists define current/current densities in artificial neural networks? Assume I have some deep network and I would like to study its dynamic/evolution in time during the training ...
2
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1answer
56 views

What tasks is Spaun 2.0 able to perform?

According to "A Large-Scale Model of the Functioning Brain" by Eliasmith et al., Spaun 1.0 was able to perform 8 distinct cognitive tasks: Copy Drawing: Given a randomly chosen handwritten digit, ...
1
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1answer
24 views

MEG from simulated neurons

Given MEG is an approximation of neuronal spiking, are there any models that associate the spiking of simulated neurons to an MEG signal? Ideally, this would be a model with some amount of behaviour (...
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1answer
36 views

Name of association phenomenon

What is the name of the problem to explain how the neural activation for "red circle and a blue triangle" is different from "blue circle and red triangle"? Just activating the neurons for "red", "blue"...
3
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1answer
100 views

What extent is non linear dynamics and chaos helpful to study brain function?

Recently I've started reading dynamical systems in neuroscience by izhikevich and was fascinated by the subject. I would like to pursue PhD in computational neuroscience after my masters. Is it worth ...
3
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1answer
79 views

What are the neurological similarities between humans and primates?

I don't know exactly what primate specie is considered to be out ancestor. But the next question regards them. Assuming that in the beginning *we considered true the remnants of many trial & ...
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1answer
28 views

Does anybody know a source having multi-electrode (several channels) recorded data of multiple Neurons (I prefer real data not artificial)?

I mean recorded data of multiple Neurons with multi-electrode. I need this data as the input for my experiment.
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2answers
160 views

Brain and General Sections

Whereabouts in the brain gets triggered/switched on when an addictive substance is ingested/taken. I'm doing an addiction study with a couple of colleagues and would like some help with it.
1
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1answer
46 views

What are the top contributions from neuroscience to AI and viceversa? How much progress has been made from the interaction between these two fields?

What are the top contributions from neuroscience to artificial intelligence and viceversa? How much progress has been made from the interaction between these two fields? Is there a formal research ...
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1answer
171 views

Does neurodynamics have any relation to psychodynamics?

From Neural oscillation - Wikipedia: Neural oscillations are commonly studied from a mathematical framework and belong to the field of "neurodynamics", an area of research in the cognitive sciences ...
2
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1answer
93 views

Why is the hopfield network a model of associative memory?

I'm struggling to understand the meaning of the term associative memory in the context of Hopfield networks. I'm not sure if associative learning is the same thing or a different thing. In associative ...
2
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2answers
149 views

Are thoughts transferred along with a brain during a brain transplantation?

If I'm transplanted with, e.g., Stephen Hawking's brain, would I start to think like him, or would I remain to think like me? On which, "thinking" ability depends , is it the physical structure of ...
2
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0answers
45 views

Is the phenomenom of “subjective consciousness” or “qualia” formally captured by any state-of-the-art Theoretical Model in Neuroscience?

Is the phenomenon of "subjective consciousness" or "qualia" formally captured or defined by any state-of-the-art Theoretical Model in Neuroscience? If so, can you share a brief summary of such ...
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1answer
28 views

Are cycles possible in circuits of neurons? [duplicate]

If we consider neurons nodes and connections between them edges, are cycles (from graph theory) are possible in the brain? To put it another way, would the signal generated from ...
3
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1answer
44 views

How long can neuron adaptation last?

One way to model a neuron which adapts to input current is an Adaptive LIF [1]. In this model, the input current is subtracted by $n$, which changes with $dn=\frac{-n}{\tau_n}dt$ [2] and $n$ is ...
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0answers
42 views

Why we construct and estimate human brain models? [closed]

Based on clinical data collected using different brain imaging, researchers build a mathematical model of the activity of the human brain like the hemodynamic model (Friston, 2000) that describes the ...
2
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1answer
51 views

In TD learning, is the weight function used as a linear filter?

In the Temporal difference learning algorithm (TD-learning), an agent seeks to predict the total value of future rewards that will be received during the current trial. The agent updates the ...
3
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1answer
71 views

Difference between brain and electronic device signals

As I understand it, a brain communicates through sending signals via ions and chemical reactions resulting in concentrations of ions, a computer sends signals by electrons. I'm really trying to do 3 ...
12
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1answer
172 views

By which neuronal mechanisms does music make us happy or sad?

There are brain regions (X) that show stronger activation for joyful music, regions (Y) that show stronger activation for sad music, and regions (Z) that show similar activation for both. Assuming ...
2
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1answer
44 views

Representations of negated propositions

The following question is quite hypothetical, and just to get an idea. Assume any model of how positive propositions $p$ are actively (opposed to synaptically) represented in a neural network, e.g. "...
4
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1answer
77 views

What is the consequences to be a person who works in theory of science?

this question rises into my head this day. First I read the comment by @mikeazo he says Do you learn best by reading or doing? That will make a difference. Also, today I had a class in ...
4
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1answer
49 views

Can the Hodgkin-Huxley neuron incorporate desensitization?

I'm studying a neuron in an organism that has the following properties: The neuron's output voltage is dependent on the strength of the stimulus, if that stimulus is applied and removed without any ...
4
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1answer
40 views

Why is positive semi definiteness a sufficient condition for Lyapunov stability of the Hopfield networks?

For a given Hopfeild network : $\tau\frac{dx}{dt} = -x + f(Wx + b) $ a general Lyapunov stability function for Hopfeild networks is : $L(x) = -\frac{1}{2}x^TWx + b^Tx + F(x)$ where $F(x) = \int^{...
3
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1answer
74 views

Can information be lost while traveling through neurotransmitters?

Can information be lost while traveling through neurotransmitters, if so then why? If information can be lost while traveling then is it possible to retransmit them and put back in order? For example ...
3
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1answer
58 views

Learning In Retina

Most of the sources studying retina seem to suggest that retinal connectome is hardwired and species dependent (like specialized vertical movement detector in small rodents). I couldn't find a single ...
7
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1answer
116 views

Question concerning Jeff Hawkins' On Intelligence

In 2004 Jeff Hawkins' book On Intelligence was widely praised. But Hawkins made some claims about artificial neural networks that seem (to me) untenable today, only 13 years later. He gives the ...
3
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1answer
314 views

Ligand-gated ion channels as operators

Isn't there a perfect analogy between ligand-gated and voltage-gated ion channels considered (mathematically) as (non-linear) operators, mapping one function (of time) to another one? Voltage-gated ...
3
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1answer
55 views

Voltage-dependent ion channels as operators

Does it make sense (or is even the standard approach) to model mathematically a voltage-dependent ion channel not as a function, that maps a voltage to a conductance ($f:\mathbb{R}\rightarrow \mathbb{...
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0answers
74 views

Hypothetical working and function of grandmother cells [closed]

I wonder, if the following model of the working and function of hypothetical grandmother cells is worthy of consideration or not (or if it is even a common view, just differently stated). I assume ...
5
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1answer
97 views

Conceptual representations in brain by distributed groups of neurons

It seems generally agreed upon that semantic concepts are distributedly represented by groups and groups of groups of neurons spread over the cortex. Disregarding the localizations, shapes and ...