I'm trying to understand why people have sometimes have the ability to sever ties with valuable connections, e.g., people that have up until that time meant a lot to them. Colloquially, people use the term "throw it all away", and I'm wondering if there's any truth to that.
Hoarders, on the other hand, can place a lot of value on objects that are generally considered to be refuse.
Looking into hoarding and it's associated disorders, I found some very recent information in Wang et al (2012) regarding some of the neural substrates of acquisitive behavior (which forms some of the physiological basis of hoarding). These researchers found activation in the orbitalfrontal cortex (OFC), a common substrate of obsessive compulsive disorder, associated with acquisitiveness, and activation in the nucleus accumbens (a motor nucleus within the basal ganglia often associated with addictive behaviors) when possessive participants valued a popular "hot" item. There was also activity in the dorsolateral prefrontal cortex, which is associated with monetary valuation of a stimulus, during "disposal" of items that they had acquired during the experiment.
Firstly, is the treatment of people like property an earmark of any notable (Axis II or otherwise) DSM disorder?
Secondly, in the case where we assume those that do treat others as property to be acquired and disposed of accordingly, do these same anatomical regions in the OFC govern this behavior?
Wang, J.M., Seidler, R.D., et al (2012),The neural bases of acquisitiveness: Decisions to acquire and discard everyday goods differ across frames, items, and individuals. Neuropsychologia, 50:939– 948