8

Short answer Don't believe everything you read. Background The article cited (Kirsch, 2014) appears in a German journal with a mediocre impact factor. Not the most convincing platform. I'll cite parts of the abstract, starting with But analyses of the published data and the unpublished data that were hidden by drug companies reveals that most (if ...


6

I'm guessing you don't want to generally increase the level of those chemicals in the brain, just in the reward-motivation area. In order to do so, you need to be rewarded and motivated, obviously. The learning need to be exciting, with feedback and reinforcement. Socializing it will help, too. There is a relatively new topic, called gameificatin, that try ...


6

When one is either learning or working with a new concept that is - complex, untangle, counter-intuitive, tedious, multi-dimensional, boring and difficult, it appears mood is altered to a lower state, very similar to that of a depressive state, however is temporary, until another concepts comes along (still new) that is simple, clear and straight ...


3

Why might sleeping on the floor alleviate PTSD symptoms? Question: Does sleeping on the floor have similar neurotransmitter effects, as sleeping under a weighted blanket might? Psychiatrically, would it be expected that a person having PTSD would find similar results sleeping under a weighted blanket as they do when they sleep on the floor? There is also a ...


3

It is entirely possible to sample serotonin levels from cerebral spinal fluid (CFS) taken via a lumbar puncture, also known as a spinal tap, to the spinal column from the central nervous system (CNS). This is the most accurate method of measuring neurotransmitter levels in the brain* without risking damage to cerebral tissue, although it is safer and almost ...


2

I have what is mostly a frame-challenge to your question as an answer: the simple "neurotransmitter imbalance" hypothesis is a bit outdated, and it hasn't been strongly influential in a research context for a very long time. Rather, it is an extremely oversimplified way to try to explain that there are brain differences involved in depression: that it's a ...


2

Let me supplement Alice's nice answer with a few more points. Regarding there are antidepressants that do not enhance serotonin but suppress it. That seems to be tianeptine; it is often brought up such discussions as the counterexample to SSRIs being "real" anti-depressants. More recent research on tianeptine suggests it acts on the opioid receptors... ...


2

You say that Antidepressants [a]rise [the] amount of serotonin in blood in short period of time. However, you should take antidepressants for quite a long period of time so that it took effect. Up to 1-4 months. As I heard there is no explanation about this fact. On the one hand we know that serotonin affects our mood, on the other hand for some reason we ...


1

It seems Maté simply misread the research that he cited. The study on this, from 1984, says that Dominant male adult vervet monkeys have whole-blood serotonin concentrations approximately twice those of subordinate adult males.


1

Prozac (the generic drug fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) and is primarily prescribed as an antidepressant, but also as an anxiolytic. The side effects of fluoxetine indeed include anxiety, but this is a rare phenomenon (source: Drugs.com). The more common complaints are restlessness and skin rash. In fact, Mayo Clinic doesn't ...


1

From my limited understanding... First off, you're definitely interpreting this correctly. The authors note: […] methylation of the proximal promoter of human SLC6A4 predicts threat-related amygdala reactivity, possibly reflecting decreased serotonin transporter gene expression and, consequently, reduced regional serotonin reuptake. However, it's ...


1

This is more of a subjective opinion, (though there are some real world examples) but I feel that the concept of "gamification" (adding game-like qualities to non-gaming tasks) is quite relevant to this topic. Sites like khan academy or codecademy use this pretty effectively, and make the process of learning math or code more enjoyable because you are making ...


Only top voted, non community-wiki answers of a minimum length are eligible