Questions tagged [neuroscience]

For questions on the structure and function of the nervous system.

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3answers
179 views

Why does journaling seem to reduce stress?

When searching methods to reduce stress and discussing my problems with people I know, it was suggested to me that I journal thoughts, that is write down what worries me elaborately on paper. I ...
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1answer
501 views

Why is inward electrical current negative?

I don't really understand, why the inward current (for example, during depolarization the flow of Na+ inside the cell) is negative? In the textbooks, it is always depicted with minus values (see ...
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1answer
67 views

What is the difference between recurrent and feedback synapses?

In the paper proposing recurrent convolutional neural networks (RCNN), "Recurrent Convolutional Neural Network for Object Recognition", it is stated that "recurrent synapses typically ...
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1answer
104 views

Is there a benefit for humans to lose memory access when under elongated periods of stress?

Long term anxiety causes memory loss. Sources: https://www.calmclinic.com/anxiety/signs/memory-loss and https://now.uiowa.edu/2014/06/stress-hormone-linked-short-term-memory-loss-we-age Are there ...
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1answer
57 views

What is meant by "serotonergic" in "serotonergic psychedelics"

"Serotonergic psychedelics" is apparently a sub-class of psychedelics. Now, I believed that the pharmacological definition of psychedelics is that they all agonise 5HT receptors, especially ...
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49 views

How does loneliness impair intelligence?

With the appearance of covid-19 and the measures that many governments have took to decrease the infection rates of their governing populations loneliness has become more common. I myself find it ...
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2answers
15 views

Why both hypokinetic and hyperkinetic changes are seen in Parkinsons?

In Parkinsons disorder the substanstia nigra pars compacta get affected and there is destruction of the dopaminergic neurons, which ultimately disturbs the direct and indirect pathways. Now we know ...
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0answers
40 views

What is the permanent effect of sleep-deprivation on the brain and its cognitive function?

I know that many teenagers suffer from chronic sleep-deprivation. This varies from country to country, but it is widely known that especially students suffer from this condition. Most have a mild form ...
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29 views

Structure of synapse

When we study the structure of the chemical synapse, by default we come across Axo-dendritic synapse consisting of various cell adhesion molecules/receptors etc. (like this). However, I was ...
2
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1answer
46 views

Measuring postsynaptic potential vs action potential at axon hillock?

I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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0answers
54 views

Using Vagus Nerve Stimulation to treat Depression

I came across an article written recently concerning the use of Vagus Nerve Stimulation (VNS) to treat difficult-to-treat depression (DTD) and other mood disorders (Sackeim, et al. 2020). However, ...
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1answer
67 views

How to determine nerve conduction velocity?

Can anyone suggest good sources or papers to understand about experimental setup and procedure for measuring nerve conduction velocity for various types of neurons? I wish to learn how such ...
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1answer
61 views

Are there "place cells" for temporal encoding?

First of all, I have to say I am not a neuroscientist but I like to learn about neuroscience. I understand there are sets of neurons called "place cells" and "grid cells" which ...
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0answers
59 views

Losing self-control during drug rehab

Is there any research or theories which can prove that exercising too much self control can lead to losing one's self-control regardless the work or activity a person engages into? From an article in ...
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1answer
79 views

Neural oscillations and activity patterns

Both single neurons and groups of neurons can generate oscillatory activity spontaneously. In addition, they may show oscillatory responses to perceptual input or motor output. Even memory and ...
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1answer
133 views

The "Triune brain" model is obsolete, what is the name of the model that replaces it?

The Triune brain model suggests our brains evolved adding more layers, a lizard brain, then a mammal brain, then a new human brain. As that's false, and the same structures have become modified in ...
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48 views

Free will and neuron firing

I have been reading a lot about free will and the most recent neuroscience experiments in that field. However, one way question troubles me to which I have never been able to find any study. We know ...
2
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1answer
383 views

What are higher-level and lower-level brain functions?

The human brain can be described as a "Russian nesting doll" in the sense that the most ancient areas of the brain responsible for lower functions are located at its centre while newer ...
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0answers
29 views

Square root transformation of Poisson process. How Var[P(sqrt(lambda))] ~ 1/4?

I am working on Kaggle Neural data challenge. A number of spikes given a stimulus are Poisson distributed as $$Y_i \sim P(\lambda_i)$$ The mean and variance of any Poisson process is given as $$E[P(\...
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0answers
19 views

Different plasticity mechanisms in different species

Are the neural plasticity mechanisms behind learning essentially the same across different species? For instance, is STDP assumed to be a standard mechanism in almost anything with a brain, or is it ...
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1answer
41 views

What does the following sentence mean? I don't understand what they are referring to when they say "saturating concentrations" and "basal conditions"?

Here is the quote: "Because BH4 is not present in saturating concentrations under basal conditions, it is crucial in regulating TH activity." This is from Fundamental Neuroscience, page 121.
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67 views

Rate of Change in Neural Plasticity

I read that children brain has more neural plasticity compared to adults, with the possible explanation as appeared in this question, pertaining to synaptic changes, where if you learn something, the ...
2
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1answer
87 views

Types of receptors on a single synapse or neuron

I have been googling and couldn't find the answer to these questions. For a given synapse, can a post-synaptic neuron have multiple types of receptors for different neurotransmitters or is typically ...
2
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1answer
23 views

research based criteria domain and DSM5

Is there any major difference between the two classification systems ? and why is there no awareness as of yet about research based domain for classifying mental disorders when it for the larger part ...
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0answers
16 views

Do stronger emotions take longer to process with dreams?

One theory of dreams is they help us process strong experiences. So I wondered whether one needs a longer sleep after some strong experiences partly to give the brain longer to complete the healing/...
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72 views

How does the brain interpret electrical brain stimulation?

I believe I understand the natural path, in which stimuli appear and by neural plasticity our brains "learn" these stimuli. I recently learned about electrical brain stimulation and I was ...
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19 views

How does Functional Electrical Stimulation (FES) restore motor functions and non-motor functions in SCI patients

I am an engineer dealing with Brain-Computer Interface, and at the moment, in a clinical context. One area which I came across was rehabilitation for patients suffering from Spinal Cord Injuries or ...
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0answers
15 views

Do neurons have a single transmitters vesicle per synapse they have?

Do neurons have a single transmitters vesicle per synapse they have? So when they will be activated, each transmitter vesicle is going to one synapse. Or is it that neurons release some amount of ...
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0answers
63 views

Do all neurons have a "job", or are some waiting to be assigned for a novel stimuli to appear?

Do all neurons have something to do (i.e. all are activated for some known stimuli), and when a novel stimuli appear some of them change in some way so we can learn it? Or is it that we have "new&...
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18 views

How does pattern separation works?

I found an article that stated: "Researchers think neurogenesis helps the brain distinguish between two very similar objects or events, a phenomenon called pattern separation. According to one ...
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1answer
60 views

How do neurons know where to send transmitters?

If a single neuron can have thousands of synapses with other neurons, how do each neuron "knows" to which further neuron to send transmitters? i.e. selectivity
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1answer
52 views

Reaction when light is turning on and off

This question comes from a personal experience I've had over the last few days, 'experimenting' on my own. I have a light bulb in a room that is turning on and off periodically, let's say per second. ...
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2answers
68 views

How to take advantage of the withdrawal symptoms of antidopaminergics?

So this may be a stupid question as I am not trained in neuroscience or psychology at all, but I had an idea about a somewhat counterintuitive approach to psychotropics and was wondering whether if it ...
2
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2answers
79 views

In principle, could a brain be rewired to experience more pleasure and/or pain?

I'm not sure if these are two separate questions, but I'm curious: in theory, could an existing adult mind/brain be modified to perceive pleasure/pain signals more intensely than otherwise? Without ...
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0answers
40 views

Are there any ways to naturally speed up my reaction speed without any drugs?

I play a lot of video-games and did some research online and came to the conclussion that a certain set of things are linked to an above average reaction speed and an general improved cognitive ...
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2answers
67 views

Memory game - short or long-term memory?

There is a game where "a suitcase is packed" and you have to remember all the words or objects that are packed into the suitcase. Each participant adds a new word to the "chain of words&...
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1answer
43 views

What is the meaning of “the inner leaflet of their lipid bilayer corresponds to the outer leaflet of the plasmalemma.”

The whole quote is, “Their lumen corresponds topologically to the outside of the cell; consequently, the inner leaflet of their lipid bilayer corresponds to the outer leaflet of the plasmalemma.” The “...
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1answer
59 views

Will smoking marijuana lightly during teens cause developmental damage to the brain?

If someone were to smoke marijuana lightly during his teens and stop abruptly in his adulthood. Would he suffer from Some type of damage to his short term memory/iq and if so can the damage be ...
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What provides regular neuron spikes for internal urethral sphincter to regularly reclench?

This "Scishow" video is about internal and external anal sphincters, its length is just 3:51. The speaker, Hank Green, says: The muscle that keeps things from leaking out of your body, your ...
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0answers
26 views

If exactly one neuron magically disappeared from my brain, would my thoughts be significantly different?

If exactly one neuron magically disappeared from my brain, would my thoughts be significantly different? One can ask an analogous question about a single neuron (and/or its synapses) being magically ...
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0answers
45 views

Sleep/Dream and Logical Decisions

I discovered that sleep tends to mitigate the 'stress' that one gets by trying to deal with logical problems like work related tasks and general daily life tasks. Does sleep do this by removing the ...
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1answer
33 views

How to handle single trial ERP (P300)

I am learning to work with EEG data in young and elderly subjects. The goal is to find differences in P300 (amplitude & latency) between both age groups during learning. I analyzed the data based ...
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0answers
19 views

Why is a low threshold necessary for generating an action potential?

On page 32 of "Principles of Neural Science," it sates that, "...the initial segment of the axon has the highest density of voltage-sensitive Na+ channels and therefore the lowest ...
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0answers
34 views

Biological Neural Network Modification to Unlearn Understandings

Lets assume that a person grows up thinking that religion X is true religion. So he builds up a profile in ones head and when notion of religion X appears the neurons that is related are fired, giving ...
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0answers
29 views

Is there a neurological explanation of acquired tastes?

People acquire tastes through exposure. This includes the "mere exposure effect" (https://en.wikipedia.org/wiki/Mere-exposure_effect). Also, music heard more often are more likely to sound ...
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1answer
100 views

Why can’t my eyes gaze around at a constant rate?

I’ve wondered about this for quite a long time, but never thought to ask it anywhere: I’m assuming most people know what it’s like to watch a bird flying by, you can steadily concentrate as the bird ...
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0answers
11 views

Interpreting FURA depolarization/calcium assay

I did a depolarization experiment that compared a mock-treated cell line with a treated line. One part of the results are easy to interpret: Treatment resulted in lower 350/380 ratios along the length ...
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0answers
11 views

What is the size, volume, dimensions etc. of the central lateral nucleus in the anterior intralaminar thalamus in humans?

I have been searching extensively on the internet and journal articles for the size, volume, dimensions, etc. of the central lateral nucleus in the anterior intralaminar thalamus in humans but have ...
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1answer
59 views

How is Pain Subjective and Different from Nociception

So pain is the sensory feeling that tells indiviual that something bad at some part of the body has happened. What I fail to understand is how is pain subjective? If we have touch receptors in the ...
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0answers
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Is there any correlation between conection and function?

I have been searching why different functions exist in even a similar structure cortex. The first reason is differences in cortical neuron density. The neuronal density contour plot (Fig. 1D) reveals ...

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