Questions tagged [neuroscience]

For questions on the structure and function of the nervous system.

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74 views

The “Triune brain” model is obsolete, what is the name of the model that replaces it?

The Triune brain model suggests our brains evolved adding more layers, a lizard brain, then a mammal brain, then a new human brain. As that's false, and the same structures have become modified in ...
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457 views

At what impedances should one gold plate 12.5-µm diameter nichrome wire tetrodes for targeting different brain areas?

Extracellular electrophysiological recordings of rodent brains using tetrodes requires plating them with gold solution in order to achieve appropriate impedances. How does the ideal plating ...
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Anyone on Jaak Panksepp’s Affective Neuroscience 7 Emotional Brain model for therapy?

Anyone here have experience in the therapeutic use of Jaak Panksepp’s Affective Neuroscience 7 Emotional Brain model for LOSS and other emotional-behavioral challenges?
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What messages sent to the brain are life or death concerns?

I have a science research and my professor told me to research about the brain and this question popped out and after so much time of researching I couldn’t find an answer. Does anyone of you guys ...
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887 views

Modern replacement for Panksepp's “Affective Neuroscience” book?

Jaak Panksepp's book (Amazon link here) is a phenomenal and highly readable systems-based introduction to not only affective neuroscience, but the neuroscience of motivation in general. The problem ...
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How much credence can you give to human cognitive studies using mice?

This question is concerning the question, How does the brain’s visual memory work? and the Neuroscience News (2020) article linked in an answer, talking about false memories. I have discussed false ...
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2answers
101 views

Is it true that mirror neurons can make a man with an amputated arm feel sensation just by looking at someone else's arm, like Ramachandran said?

In this Ted Talk Ramachandran sais that mirror neurons can make a person with an amputated arm feel sensation, is it true? And if so, why doesn't the brain feel a sensation by looking at someone else'...
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32 views

Does being sporty affect a person's reaction to emergency situations?

I have always been quite sporty, and I tend to remain relatively calm and composed in emergency or high stress situations. From my personal experience, people who are quite sporty and have been in ...
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45 views

What is the neurological basis for the association between Bipolar type 2 and autism spectrum disorder (ASD)?

Bipolar disorder type 2 and autism spectrum disorder (ASD) is regularly seen together. What is the neurological explanation for this?
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59 views

What is the role of dendrites in neural computation?

I read this article: https://news.mit.edu/2019/neurons-dendrite-role-computation-0606 My question is about this: “One hypothesis is that dendritic activity will actually sharpen up for representing ...
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41 views

Does nostalgia contribute to overrating past experiences?

We all have something in our lives that we are sentimental about, and even a glimpse of that object/idea can bring back happy memories. And nostalgia makes the remembrances of those experiences feel ...
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54 views

Neurologically, how does a thought terminate?

What prevents my brain from holding the same thought forever, like a frozen computer? How do neurons terminate a firing pattern and move onto the next?
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Do people with sociopathy, neuroticism need medical attention?

Do people with sociopathy, neuroticism need medical attention? I thought people with dark traits don't need medication unless it causes them to have problem functioning in society like working with ...
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35 views

What scientific evidence is there for the definable real world quality of redness independent our perception?

'With light poise and counter-poise, Nature oscillates within prescribed limits. Yet thus all arise the varieties and conditions of the phenomena which are present to us in space and time.' - Goethe ...
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107 views

What neurological processes occur with 'revulsion'?

As the title asks, what neurological processes occur when we feel revulsion? By revulsion, I mean the involuntary and voluntary physical and psychological responses far stronger than the aversion ...
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1answer
62 views

What comes first? Thought or electric activity?

Our thoughts are basically the result of the electro chemical activity which are happening in our neurons. The signals sent by different neurons to each other back and forth create a pattern which we ...
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184 views

Is it true that old people loose the ability think creatively/ formulate new ideas

My friend said something about that people get older than 50 loose the ability to think creatively and formulate new ideas. There is also a saying like “stuck in his ways” and people say the “older ...
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47 views

What are ERP components such as N400?

A lot of research uses ERP, which is time-locked EEG. I am reading about semantic and syntactic anomalies. So when a semantic anomaly occurs there is supposed to be a negative peak in ERP at 400ms. I ...
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1answer
159 views

Kinetic synesthesia evoked by abstract thoughts?

Can the experience of movement when mentally visualizing the network/structure of the code of a complex application, and the information that flows through the network as a programmer be a kind of ...
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1answer
89 views

Neurological explanation for differences in what motivates runners?

I have noticed differences between how my friends and I are motivated with regards to exercise, and would like to better understand what is influencing this difference psychologically. Personally, ...
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1answer
93 views

Why does journaling seem to reduce stress?

When searching methods to reduce stress and discussing my problems with people I know, it was suggested to me that I journal thoughts, that is write down what worries me elaborately on paper. I ...
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240 views

Why aren't any advancements being made in physically diagnosing Bipolar and other psychiatric disorders?

I was involved in a discussion where somebody had asked if others had thoughts of doing risky things during their manic episodes. Two people commented, including myself. I worried that only relying on ...
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1answer
64 views

Is it possible to get good hallucination while suffering from schizophrenia?

Schizophrenia : A disorder that affects a person's ability to think, feel and behave clearly. The exact cause of schizophrenia isn't known, but a combination of genetics, environment and altered brain ...
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51 views

What is “required reading” in training that describe mechanisms behind learning?

I've previously studied spiking neural networks in the context of machine learning applications and I'm interested in gaining a better understanding of the biology of the brain. My goal is to ...
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10 views

Is there a mechanism in neurons to temporarily increase membrane resistance?

I was just learning how electrical signals travel down the neuron and learned that electrical signal flowing out through the membrane significantly hinders the voltage to move down the axon. This ...
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1answer
26 views

How does the neuron recover from hyperpolarizationn?

Assume we're at the state where the potassium gates have closed. Inside the membrane should still be more negative relative to its resting potential. This source claims that the sodium-potassium pump ...
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Can we over sensitise people

Is there evidence that "over sensitivising" an indvidual (eg adolescent) makes them less resilient? So to explain, if we ask an individual repeatedly how they feel and if they have been ...
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93 views

Is there a benefit for humans to lose memory access when under elongated periods of stress?

Long term anxiety causes memory loss. Sources: https://www.calmclinic.com/anxiety/signs/memory-loss and https://now.uiowa.edu/2014/06/stress-hormone-linked-short-term-memory-loss-we-age Are there ...
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Question about nest cell

I'm reading the PNAS paper Neural encoding of the concept of nest in the mouse brain by Lin et al. 2007 A certain 'nest cell' is described in the paper that fires only when the mouse approaches its ...
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Is the GMC (ganglion mother cell) in Drosphila the same thing as the basal daughter cell? Does a highly active Notch pathway obstruct cell division?

"Numb acts as a negative regulator of the Notch pathway (discussed above), which keeps Notch pathway activity low in the GMC. Low Notch activity causes the de-repression of proneural genes, as ...
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Can the administration of self-report measures of craving prompt participants with addiction to experience craving during the experiment?

My research focuses on measuring the neural correlates (through resting-state EEG) pre-post an improvisational music therapy session (MT sessions) in clients with substance misuse. One of my variable ...
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Can some stimulants take the place of others?

I learned in class recently that neuroreceptors can cause different chemical changes in the brain and nervous system. I was told that stimulants increase heart rate and awareness, which got me ...
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Neuroscience & Epistemology - Feedback in Hermeneutic circle of Theory and Experiment

How good is neuroscience at closing this Hermeneutic circle in the Philosophy of science? I am referring to the interplay of theory and experiment. This is depicted in the following figure: ...
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3answers
571 views

Does the mind create the body?

Everything we perceive is through the 5 senses. That means the body which is perceived through sense of feeling and seeing is also formed as an image in mind or brain? Is it correct that it is either ...
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Is there a formal definition for “axon terminal field”?

I would be interested in a formal definition for this term, or at least a paper which describes this notion explicitly (instead of just using the term). Many papers seem to use it, but I haven't ...
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33 views

Endogenous Neural Activity

Could someone explain to me what exactly is endogenous neural activity? I am reading a lot of research papers, and I want to understand things thoroughly. Thanks for the response in advance. This is ...
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1answer
35 views

Measuring postsynaptic potential vs action potential at axon hillock?

I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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20 views

What's the relation between distorted(REM) sleep and creativity?

I was recently listening to Huberman's podcast where he said that disturbed REM sleep causes people to make odd connections and I was wondering if there is any relation between distorted REM sleep and ...
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22 views

Funiculus vs. fasciculus vs. nerve

After reading through a bunch of sources, I'm quite confused as to these three terms. Wikipedia suggests that a funiculus is a bundle of axons, and a fasciculus can contain multiple funiculi. On the ...
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23 views

Can the Conscious Competence Learning Model be applied to emotion regulation

Can the Conscious Competence Learning Model be applied to emotion regulation? As you activate the parasympathetic nervous system by utilizing techniques such as meditation your overall emotion ...
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1answer
766 views

What would happen to the human brain after running out of memory?

According to this answer humans have enough memory to store 300 years of TV shows. However, of course, it is disputable, as storage system would be completely different from storing TV shows (videos) ...
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117 views

what causes an action potential to propagate exactly and why should it propagate?

Hello I am taking a neurophysiology course and learned about the action potential and that it propagates in one direction from axon hillock down along the axon. I understand that action potential is ...
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201 views

Why is inward electrical current negative?

I don't really understand, why the inward current (for example, during depolarization the flow of Na+ inside the cell) is negative? In the textbooks, it is always depicted with minus values (see ...
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1answer
51 views

Types of receptors on a single synapse or neuron

I have been googling and couldn't find the answer to these questions. For a given synapse, can a post-synaptic neuron have multiple types of receptors for different neurotransmitters or is typically ...
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1answer
63 views

What is the difference between recurrent and feedback synapses?

In the paper proposing recurrent convolutional neural networks (RCNN), "Recurrent Convolutional Neural Network for Object Recognition", it is stated that "recurrent synapses typically ...
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2answers
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Why both hypokinetic and hyperkinetic changes are seen in Parkinsons?

In Parkinsons disorder the substanstia nigra pars compacta get affected and there is destruction of the dopaminergic neurons, which ultimately disturbs the direct and indirect pathways. Now we know ...
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51 views

What is meant by “serotonergic” in “serotonergic psychedelics”

"Serotonergic psychedelics" is apparently a sub-class of psychedelics. Now, I believed that the pharmacological definition of psychedelics is that they all agonise 5HT receptors, especially ...
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44 views

How does loneliness impair intelligence?

With the appearance of covid-19 and the measures that many governments have took to decrease the infection rates of their governing populations loneliness has become more common. I myself find it ...
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30 views

What is the permanent effect of sleep-deprivation on the brain and its cognitive function?

I know that many teenagers suffer from chronic sleep-deprivation. This varies from country to country, but it is widely known that especially students suffer from this condition. Most have a mild form ...
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Structure of synapse

When we study the structure of the chemical synapse, by default we come across Axo-dendritic synapse consisting of various cell adhesion molecules/receptors etc. (like this). However, I was ...

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