Questions tagged [neuroscience]

For questions on the structure and function of the nervous system.

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Why are thicker nerve fibers more easy to stimulate?

experiments have shown that thicker nerve fibers are more easy to stimulate and myelinated ones are more easy to stimulate than unmyelinated ones. increasing diameter means lower axial resistance from ...
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where is the second electrode in case of electrostimulation

With electrostimulation or functional electrostimulation, a response from the neuron is generated by electrical impulses. But I always read, for example, that a stimulating electrode is above position ...
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Mechanism of ketamine in treatment of depression and anxiety?

What are the mechanisms by which ketamine reduces the symptoms of depression and anxiety? E.g. https://clinicaltrials.gov/ct2/show/NCT00088699.
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Noise in Neurons (channel noise)

If you stimulate neurons 10 times with the same electrical pulse, you will get a different response 10 times. For example, if you apply a pulse near the threshold, you may get 7 APs, which are ...
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1answer
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What are the neurological differences between varying types of love?

It stands to reason that the biochemical cascade involved when a person experiences love, gives a feeling of well-being and drive. Studies in neuroscience have involved chemicals that are present ...
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At what point do dopamine/serotonin receptors become downregulated/upregulated?

It's well known that behaviors like pornography viewing lead to dopamine receptor downregulation to compensate for the extreme stimulation. Obviously, drugs like methamphetamine would lead to an even ...
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1answer
30 views

How do the outer hair cells amplify the traveling wave?

Depending on the movement frequency, outer hair cells can stretch and contract, amplifying the amplitude of the traveling wave at the basilar membrane. How can they do this exactly? what is the point ...
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1answer
23 views

What are the advantages of biphasic nerve stimulation?

One can stimulate nerves or muscle cells in different ways - with single-phase or multiphase pulses, cathodic or anodic, and via surface electrodes or implanted ones. What exactly is the advantage of ...
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Why are some events not memories? [closed]

I have an excellent memory. I remember little details that can amaze my family. My memories are often as vivid as the experience I once had. However, my memory does have holes in it as I was never ...
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1answer
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Deflection of the basilar membrane

The basilar membrane becomes thicker and heavier from the basal end to the apical upper end - this is why high frequencies are perceived in the lower range and low frequencies in the upper range. But ...
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Searching for finding the similarity of the Autism verbal brain functionality with the AI' Pix2pix Model [closed]

I have seen the below Autism simulation's video, which show some sound stimulation of visual functionality of brain: So I am trying to find some connection between the AI models used in Pix2Pix ...
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1answer
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Is there a theoretical maximum for IQ?

In "Eugenics: A Reassessment" Richard Lynn writes: The intelligence level of the population would be expected to stabilize at its theoretical maximum of around 200 after six or seven ...
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Is there a Big Five personality assessment under an open-commercial license?

I am currently working on a project with a few students. It's an app that can test the big 5 personality test. The problem is, I am having trouble finding one that is under an open license and that we ...
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Sound decomposition of the brain [closed]

The listening process is really very complex and I would like to ask if I understand it correctly. A sound source changes the air pressure, which is otherwise 101.325 Pascal, whereby the audible ...
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Does the brain send signals continuously to muscles during movement?

If I make one swift movement with my arm, like just raising it, is my brain continuously sending signals throughout the whole movement? Or does it just send signals one time? The latter seems to make ...
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2answers
467 views

Is the split-brain, dual consciousness experiment from Rhawn Joseph valid?

I have been reading about the problem of possible dual consciousness in split brain patients and I came across this wikipedia page. In the "other experiments" section, the two last ...
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3answers
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Why does journaling seem to reduce stress?

When searching methods to reduce stress and discussing my problems with people I know, it was suggested to me that I journal thoughts, that is write down what worries me elaborately on paper. I ...
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1answer
440 views

Jung's Anima and Neurological Basis in Split-Brain Patients; Left-Persona and Right-Anima

So, having skimmed some studies on split-brain patients, it makes me wonder about the whole "left-brain/right-brain" dichotomy that made its rounds in public perception some time ago. I'm not sure ...
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1answer
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Do induced brain wave patterns give the same cognitive and perceptual consequences as those that arise naturally? [duplicate]

What I mean to ask by this particular question is that, are the effects resulting from neural interactions in the brain that cause the emergence of certain behaviours, with the neural frequencies in ...
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1answer
67 views

What is the role of dendrites in neural computation?

I read this article: https://news.mit.edu/2019/neurons-dendrite-role-computation-0606 My question is about this: “One hypothesis is that dendritic activity will actually sharpen up for representing ...
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Does the increase (i.e. more positive) of an equilibrium potential always cause the membrane potential to increase (i.e. the cell depolarizes)?

I am a little bit confused. I know that for potassium, when less ions are going down the concentration gradient, Ek increases and the neuron becomes depolarized. However, I am also aware that if Ena ...
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1answer
58 views

What's the exact definition of a cognitive mechanism?

I've been trying to get to a specific definition of a cognitive mechanism, but googling it surprisingly didn't give me anything. The only things I've found out are : How to know if something can be ...
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What are the values of the absolute intracellular and absolute extracellular potentials in a neuron?

Most texts on neurons give the value of the membrane potential and do not state the absolute values of the intracellular and extracellular potentials in a neuron. I understand that this is because the ...
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1answer
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What is the meanning of an x-expressing neuron, with x = some protein?

I'm studying a neuroscientific paper, and in it the authors state that "defensive behaviors are mediated by a BLA population of magnocellular R-spondin 2-expressing (RSPO2⁺) neurons". I know ...
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What happens to the motor region in the brain if people get paralysed?

Imagine a person that is paralysed because the connection between the motor region in the cortex and the motor apparatus in the body (neurons) is comprised. What happens to the neurons that were ...
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655 views

What is the neurological mechanism responsible for losing one's temper?

I'd imagine that losing one's temper is quite normal, I can not think of anyone who has not experienced it. For me, it is rare, but does happen, I find that there can be 3 broad stages occur (note: ...
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Why is it only positive charge that gets injected into a neuron when we inject a current into it?

Learning about the basics of theoretical neuroscience from the youtube lectures from Michale Fee's introduction to neural computation course. We're considering a very simplified model of a neuron, ...
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1answer
104 views

Neurological explanation for differences in what motivates runners?

I have noticed differences between how my friends and I are motivated with regards to exercise, and would like to better understand what is influencing this difference psychologically. Personally, ...
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1answer
64 views

What is the cochlear frequency response by number of hair cells?

I am trying to recreate the cochlea/basilar membrane response to sound and want to know how the hair cells are bucketed or binned by frequency, so an ideal list would be something like 10 kHz - 12 kHz:...
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1answer
63 views

Lunar cycles linked with mental health issues?

From what I can find... Anecdotally, my mother used to work in nursing homes for the elderly and found that around the full moon, patients slept less and were more agitated. Anecdotal evidence ...
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What part of the brain is different when you have a really good memory?

I wanted to know how the brain of someone with a great memory differs from that of an average memory. This memory does not have to be eidetic, or highly superior autographical or even hyperthymesia. ...
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What is meant by the so often heard phrase that we only use 12% of the brain?

I have heard it so often that we use only 12% of our brain. I truly don't understand this. All neurons in the brain are are firing within a small amount of time. Even in my sleep this is going on. ...
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What is the name of this disorder or syndrome? [closed]

I am referring to a behavior of some in this case(a Gamer), who's bought a bad game or something similar to someone who loves to spend time enjoying and playing something, but the "game" is ...
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1answer
66 views

What is the difference between the processing of visual information and auditory information?

We can read: The visual cortex is located in the occipital lobe of the brain and is primarily responsible for interpreting and processing visual information received from the eyes. The amount of ...
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Difference in neural activity of a thought vs. a memory

I want to understand the difference in neural activity between a "thought" and a "memory impression". Is it a "thought" while the neural activity is present in working ...
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50 views

How is the brain divided in parts?

Now I can imagine the body being separated in parts. There is the liver, the bones, the skin, the eyes, the kidneys, the feet, the legs, or the brain. All these sub-units work together coherently and ...
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Schizophrenia and the second personality [closed]

I was diagnosed with schizophrenia and searched for information about this disease and found it matches what happened to me but there is something I did not find in the articles is that I was feeling ...
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1answer
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What are presynaptic puncta?

What are presynaptic puncta? And what makes them different from presynaptic terminals? I encountered the term puncta in the following article: Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, ...
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1answer
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Measuring postsynaptic potential vs action potential at axon hillock?

I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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Does the sensation of pain arise in the brain? [duplicate]

I can feel pain in my arm or in my brain. I have read that you can feel a phantom pain. As if the pain exists outside the body. There is a related process in the brain but the feeling itself seems to ...
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From a neuroscientific point of view does internet gaming disorder have the same effect on the brain as porn addiction?

Wang, et al. (2015) proved that among people with internet gaming disorder GMV (Gray Matter Volume) of the bilateral anterior cingulate cortex (ACC), precuneus, supplementary motor area (SMA), ...
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1answer
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Are there equivalent calcium imaging molecules that fluoresce in the presence of neurotransmitters between axons?

Molecules like GCaMP fluoresce when calcium ions attach to them. I was wondering if this can work with the other neurotransmitters in the brain or compounds that transmit signals outside of neurons.
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How close are fluorescent dyes to individual neurons in two photon microscopy?

Considering the minute electrical excitation produced by neural cells needed to excite fluorescent dyes, how close are they to these cells, considering that being too close will disrupt cell processes....
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Does anyone know of more predictable chronic mild stress articles? [closed]

I am trying to write a paper on predictable stress. These are the only references I can find. Do you know of more articles like these? Thank you very much. Predictable chronic mild stress promotes ...
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1answer
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What is the actual interpretation of the "correlation of a connection between neurons"?

I am student of Mathematics who is currently studying the utility of Algebraic Topology in the field of Neuroscience. In the paper I am reading (Reimann et al 2017) the authors explain that for ...
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1answer
43 views

Does being sporty affect a person's reaction to emergency situations?

I have always been quite sporty, and I tend to remain relatively calm and composed in emergency or high stress situations. From my personal experience, people who are quite sporty and have been in ...
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1answer
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What is the neurobiological mechanism behind masochism?

I tried to search in textbooks and papers but barely found any concrete answer to which exact mechanism is behind non-intuitive transition from pain to pleasure. Does it have something to do with: ...
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2answers
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Why both hypokinetic and hyperkinetic changes are seen in Parkinsons?

In Parkinsons disorder the substanstia nigra pars compacta get affected and there is destruction of the dopaminergic neurons, which ultimately disturbs the direct and indirect pathways. Now we know ...
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130 views

The "Triune brain" model is obsolete, what is the name of the model that replaces it?

The Triune brain model suggests our brains evolved adding more layers, a lizard brain, then a mammal brain, then a new human brain. As that's false, and the same structures have become modified in ...
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488 views

At what impedances should one gold plate 12.5-µm diameter nichrome wire tetrodes for targeting different brain areas?

Extracellular electrophysiological recordings of rodent brains using tetrodes requires plating them with gold solution in order to achieve appropriate impedances. How does the ideal plating ...

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