Questions tagged [neurophysiology]

The study of the physiology of the nervous system, with emphasis on transcellular communication, and cellular and molecular processes involved in neural communication.

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Understanding ketamine, the role of synatptic placitity in Major Depression

I am having a bit of an issue with my intuitive understanding of Ketamine's newfound role in treating depression. It is my understanding that Ketamine works by allowing synaptogenesis. The evidence ...
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What are the necessary preconditions for the emergence of a conscience?

I am aware of 2 brain anomalies that seem to be associated with the non-emergence of a conscience. One is associated with psychopathy. The other is associated with narcissism. psychopathy: My ...
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Do neurons involved in reflex movements process information or they just transmit a signal?

According to Reflex A reflex, or reflex action, is an involuntary and nearly instantaneous movement in response to a stimulus. A reflex is made possible by neural pathways called reflex arcs which ...
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High blood pressure can lead to anxiety?

I know that anxiety leads to high blood pressure due to elevations of adrenaline. It also can also increase cortisol levels which as the Mayo Clinic points out: curbs functions that would be ...
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Using Vagus Nerve Stimulation to treat Depression

I came across an article written recently concerning the use of Vagus Nerve Stimulation (VNS) to treat difficult-to-treat depression (DTD) and other mood disorders (Sackeim, et al. 2020). However, ...
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Will studying formal logic improves logical reasoning?

Reason for asking question: I am looking to see if there is any good empirical evidence or study that shows or suggests that studying former logic or maybe informal logic would actually improve ...
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338 views

What neural mechanism explains the phenomenon that bad memories fade faster than good ones?

Several studies have suggested that negative memories fade faster than positive memories: Walker, Vogl and Thompson (1997) had the subjects kept dairy during a 3-month period, and rated the events on ...
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What is the medullary bulb transition?

Does "medullary bulb transition" make sense in neuroanatomy internattionally or is it a Brazilian invention and there is no term like that in English? What is then the difference of the &...
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Neuron specialization in the Visual System

Can someone point me to a good resource to explain how neurons in the visual system become sensitive to visual features? I understand that specific neurons fire for things like direction of motion, ...
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62 views

What are the neuroscience research findings on the importance of breaks in cognitive function and specifically learning?

When I say breaks I mean breaks between periods of the same course, breaks between two distinct courses, single days of, weekends, couple days of, few days of, longer periods of holidays of duration ...
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690 views

What happens in the brain during mid-life crisis?

I was just told by an elder that midlife crisis occurs during an adult stage and it is a time whereby an adult starts having several thoughts concerning his/her life. After my research, I found out ...
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Minimum constant neuron firing rate

Please forgive what may be an elementary question for many of you. I am trying to understand the range of firing rates in an idealized neuron. I understand what governs the maximum firing rate of a ...
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242 views

What's the pathfinding algorithm the human brain uses?

I was trying to build a software simulation of people using different pathways in a city to get from point A to point B. I do know the Dijkstra's algorithm and the A* algorithm, but what they do is to ...
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49 views

Can non-spiking neurons have a sustained synaptic output current?

I'm trying to better understand neural models, specifically non-spiking neurons in invertebrate motor control circuits. I know that a spiking neuron produces spikes in membrane potential that rapidly ...
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What are the names of the white matter tracts in the cortico-ventral basal ganglia circuit?

I am looking at diffusion tensor imaging (DTI) data. The data are clustered by regions of interest (ROIs). The clusters have locations with names, which I have listed below. Which location names ...
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Measuring postsynaptic potential vs action potential at axon hillock?

I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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Can some stimulants take the place of others?

I learned in class recently that neuroreceptors can cause different chemical changes in the brain and nervous system. I was told that stimulants increase heart rate and awareness, which got me ...
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32 views

Has anyone tried using functional near-infrared spectropathy to quantitively measure sodium concentrations in the brain?

Functional near-infrared spectropathy "fNIRS", is a biophysics/medical technique that uses the near-infrared part of the electromagnetic spectrum (around 680nm to 810nm in wavelength) to ...
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What is the size, volume, dimensions etc. of the central lateral nucleus in the anterior intralaminar thalamus in humans?

I have been searching extensively on the internet and journal articles for the size, volume, dimensions, etc. of the central lateral nucleus in the anterior intralaminar thalamus in humans but have ...
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25 views

What is the neuroscience behind copying dialect?

So everybody raised in the same area speaks with the same dialect, why is it so? What is the neuroscience behind this phenomenon?
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How does the body respond to having excess levels of neuronal, not synaptic, serotonin?

If a person consumes large amounts of 5-HTP or SAM-e resulting in elevated serotonin levels in their synaptic vesicles, how is this excess offloaded? What is the average rate of clearance? All the ...
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Why is median motor nerve conduction velocity about 50 m/s?

I recently started reading Fitzgerald's clinical neuroanatomy and neuroscience (Mtui, et al. 2015) and reached chapter 12, electrodiagnostic examination, yesterday. The chapter deals, i.a., with nerve ...
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Can reuptake absorb a selective or non-selective agonist?

For example, a lot of antipsychotics are chemically similar to serotonin, and at least partially trigger certain types of serotonin receptors. Is there any evidence to suggest that, because of their ...
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42 views

Neurogensis in CNS invloves apoptosis of scar cells?

Say there's neurogensis in a brain area that seems to "allow" it, like the Hipocampus, Striatum, and so forth. Does this neurogensis might be preceded in the apoptosis of scar cells, and then, in the ...
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where is the second electrode in case of electrostimulation

With electrostimulation or functional electrostimulation, a response from the neuron is generated by electrical impulses. But I always read, for example, that a stimulating electrode is above position ...
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37 views

What are the values of the absolute intracellular and absolute extracellular potentials in a neuron?

Most texts on neurons give the value of the membrane potential and do not state the absolute values of the intracellular and extracellular potentials in a neuron. I understand that this is because the ...
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Is there a no-change plateau in the bidirectional calmoduline regulated plasticity proposed by Lisman in 1989?

Reading the paper "A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory" Lisman 1989, especially figure 2, it gives the impression that in the bidirectional ...
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Structure of synapse

When we study the structure of the chemical synapse, by default we come across Axo-dendritic synapse consisting of various cell adhesion molecules/receptors etc. (like this). However, I was ...
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48 views

Free will and neuron firing

I have been reading a lot about free will and the most recent neuroscience experiments in that field. However, one way question troubles me to which I have never been able to find any study. We know ...
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Interpreting FURA depolarization/calcium assay

I did a depolarization experiment that compared a mock-treated cell line with a treated line. One part of the results are easy to interpret: Treatment resulted in lower 350/380 ratios along the length ...
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Why are thicker nerve fibers more easy to stimulate?

experiments have shown that thicker nerve fibers are more easy to stimulate and myelinated ones are more easy to stimulate than unmyelinated ones. increasing diameter means lower axial resistance from ...