Questions tagged [neuroimaging]

For questions about techniques to directly or indirectly image the structure, function, or pharmacology of the brain.

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27
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1answer
3k views

Have the abilities of John Lorber's patients with limited cortical mass been further evaluated in adulthood?

Short of minor lesions or infarcts, most high-functioning adults have an intact cerebral cortex. Yet, a surprising result published anecdotally in Science in 1980 caused a lot of scientists to take ...
18
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2answers
1k views

Does the fusiform face area in patients with Prosopagnosia (face blindness) show lower activity under an fMRI?

I watched last night's episode of 60 minutes (and part 2) about Prosopagnosia (Face Blindness) and found it absolutely fascinating. They mentioned in the segment (Around 5:22 into the second part of ...
16
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3answers
1k views

Research suggesting conscious control over brain region activation?

Has there been any research proving, disproving, or exploring the concept of conscious activation of specific brain regions? To elaborate on this: I've read that performing processing tasks causes ...
15
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3answers
987 views

Is there a better way to describe brain activity than EEG “brain waves”

I've been reading about EEG brain waves, which are specific waveforms that are observed on the EEG output, and are usually scored by humans. This concept has been around for quite some time. Is there ...
12
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3answers
1k views

Neurotransmitter based imaging techniques

All the brain imaging techniques I know fall into two categories: Tracking blood Either by looking at the magnetic (fMRI), or near-infared absorption (diffuse optical imaging, NIRS) properties of ...
12
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2answers
850 views

What are different ways to determine centroids of fMRI activation, their drawbacks and perks?

I'm reading an older article on bilingualism (Kim, Relkin, Lee, & Hirsch, 1997) for a seminar. They were interested in the spatial separation of two languages in early and late bilinguals. They ...
12
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1answer
374 views

Can we draw conclusions about content of thoughts from neural firing patterns?

Can the neural firing patterns of animals be associated with specific kinds of thoughts? (ie Thoughts related to food, mating, or neighborly aggression?) I am curious about the speculations in ...
11
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2answers
577 views

What computerized EEG analysis algorithms are there?

I got a commercial-grade EEG headband and am trying to look at the data it outputs. The headband quantifies raw EEG signal from a single forehead dry sensor into a range of EEG bands (alpha, beta, etc)...
11
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3answers
216 views

What kinds of information can (and cannot) be extracted from connectome?

Several scientific projects are trying to map the connectome, such as The Human Connectome Project. The connectomes of other organisms, such as C. elegans, have been mapped already. Having an ...
10
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2answers
1k views

Plotting publication-quality ball-and-stick models of brain connectivity in 3D

I'm working on brain imaging (fMRI) and I'm looking for a way to plot brain effective connectivity (dynamic causal modeling) parameters between different brain regions in a 3D plot. The plotting ...
9
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1answer
2k views

What are the major structures of the medial temporal lobe?

Basic question here from a behavioral researcher: What are the major structures of the medial temporal lobe (MTL)? Can anyone link to a good diagram of these structures?
9
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2answers
338 views

What happens in the brain when conscious awareness is changed during dreaming onset?

I've long been interested in dreaming and there's a peculiar phenomenon of the very start of the dreaming process. Different people experience it differently, but even for the same person there's ...
9
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1answer
572 views

How does glial cell activity influence fMRI, EEG signals?

Glial cells comprise about 80% of the cells in the human brain. But physiological models of EEG and fMRI often relate only to neuronal activity. How do glial cells affect large-scale imaging ...
9
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1answer
104 views

Open magnetic resonance imaging datasets on psychosis?

Are there any open magnetic resonance imaging datasets of normal and healthy adults (as controls) and psychotic subjects? Such as ADNI for Alzheimer's or OASIS for aging.
8
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2answers
1k views

How do we know human brain development stops around age 25?

I've heard this stated as a fact more times than I can keep track of, but I haven't been able to find papers that actually demonstrate this. This seems to be the most cited paper on the topic, but it ...
8
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1answer
725 views

Frissons on demand

Have you ever listened to music and it gives you "chills?" This response is called a "frisson," a french word meaning "to shiver." When I want to access certain emotional and inspirationally charged ...
8
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1answer
503 views

In fMRI analyses, what is the t-test actually comparing?

In a 1st-level fMRI analysis, it is unclear to me what the t-test performed for each voxel is actually comparing. I've seen this being described in one of two different ways: The t-test estimates how ...
8
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1answer
1k views

Is there difference between a memory of a dream and memory of waking experience?

I'm very interested in dreaming and have pretty good dream recall. This makes me able to recall and distinguish hundreds of experience within my memory and label them as "dreams". I'm trying to ...
7
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2answers
238 views

Open access 7T resting-state fMRI dataset

I'm looking for an open access dataset of 7-tesla resting state fMRI images of human subjects. I've been able to find one so far (http://www.nature.com/articles/sdata201454). However, I need images ...
7
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1answer
223 views

Why “fractional” anisotropy?

Why is Fractional Anisotropy (FA), a measure in diffusion tensor imaging, called "fractional"? I'd have thought "local", i.e. voxel-wise, would have been the correct way to qualify the anisotropy that ...
7
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2answers
1k views

EEG correlates of handedness

Can any one suggest a good article about features of EEG of left-handed people? I was surprised when find that there are only few old articles about it. I find only one new article by Propper, Ruth ...
7
votes
1answer
138 views

How to stain for orexin neurons in mice?

I am interested in studying possible depletion of orexin levels in the brains of some mice, and am wondering if anyone knows of a staining substance/technique for use on slices of fixed mouse brains ...
7
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0answers
180 views

Supplementary Motor Area or Juxtapositional Lobule Cortex

Harvard-Oxford Cortical Structural Atlas now calls the 'Supplementary Motor Area' the 'Juxtapositional Lobule Cortex (formerly Supplementary Motor Cortex)'. I've looked for papers that explain the ...
6
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1answer
485 views

What does fMRI measure exactly

It is true that blood flows to wherever the brain is most activated and does fMRI measure the blood flow inside of the brain through oxygen content?
6
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1answer
1k views

Are scintillating scotomas really caused by cortical spreading depression? If so, how is this known to be true?

I have just read about a visual effect called a scintillating scotoma. Many variations occur, but scintillating scotoma usually begins as a spot of flickering light near or in the center of the ...
5
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1answer
906 views

Is it possible to detect the mental flow state with EEG?

I know that it is possible to detect "focus" with a consumer EEG with a single electrode and a reference point (ear clip), even without conductive gel, but is it possible to detect a flow state with ...
5
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2answers
641 views

Why is it hard to simulate a neuron?

I read a NY Times article about the European effort to simulate a human brain and the criticism regarding the (non-)feasibility of such an endeavor (not to mention the astronomical costs). In this ...
5
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1answer
346 views

Can tinnitus be measured with EEG or MEG?

Can tinnitus be measured with EEG or MEG (magnetoencephalography)? Is it visible in a power spectrum? In an ERP/ERF?
5
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1answer
89 views

Is there a complete connectome of a minicolumn of the neocortex?

I know that there are projects that try to map brain connectivity. My question is whether there is a dataset available with the complete connectivity of just a single minicolumn of the neocortex. ...
5
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2answers
2k views

Difference between reverse inference and decoding (e.g. MVPA) in fMRI

Reverse inference, i.e. the use of brain activation (fMRI) data to infer the engagement of a certain mental function, is heavily criticised (e.g., Poldrack 2011, Neuron). At the same time, decoding, ...
5
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1answer
51 views

Is it reasonable to have a factor with only two levels in a carry-over design for an fMRI study?

I'm planning a carry-over design for an fMRI study. To save time, since it seems that I'll need a huge number of trials for my purpose, I'm wondering if it's reasonable to have a matrix 2x3x3, ...
5
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1answer
418 views

How can I visualize DTI tractography streamlines generated from FSL's probtrackX in 3D?

I currently have track files of diffusion tensor imaging (DTI) data generated from FSL's probtrackX tractography tool. What is the best software to visualize the streamlines from FSL in 3D?
5
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0answers
121 views

Is there a tangible benefit of synchronising the sample clock to the laser pulses in a resonant scanning two-photon microscope?

NI data acquisition cards offer a possibility of synchronising data acquisition with the pulses of a 80 MHz Ti:Sapphire laser. This supposedly helps improve the signal to noise ratio, since the true ...
5
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0answers
30 views

Simultaneous DTI, structural MRI and 1H-MRS - Are there any examples of this?

I have been reading about recent articles relating to treatment resistant schizophrenia, and apparently there are a lack of studies using multimodal imaging. Initially I just thought that would be ...
5
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0answers
416 views

What are the brain regions related to tinnitus shown in this figure?

I am interested in learning about the neural mechanisms behind tinnitus, and was wondering if someone could help me to name the parts of the brain on this image that show increased activity in ...
4
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2answers
2k views

MRI images upside-down in FSLVIEW

I'm visualizing structural data in FSLVIEW, but the sagittal and coronal planes are both upside-down / not in the conventional orientation, i.e. rotated by 90º and 180º. I understand that this upside-...
4
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1answer
377 views

During body-scan ('sweeping') meditation, what does brain-imaging (e.g. fMRI) look like?

I do not know how extensive body scans have been studied with brain-imaging techniques, e.g. fMRI. Body scan is a meditation technique developed by Jon Kabat-Zinn. It was derived from a meditation ...
4
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1answer
468 views

where can i find preprocessed fmri data set for alzheimer's disease

I want to work on identification of Alzheimer's patients based on given fMRI data.Basically, I want to implement the following paper https://www.ncbi.nlm.nih.gov/pubmed/25907414. Where can I get ...
4
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1answer
380 views

What does 'Mean Diffusivity' tell me about the connectivity of cortical areas?

I am reading an article about changes in thalamic volume and connections in relation to age and I understand that thalamic volume decreases with age. The authors find that mean diffusivity (MD) in ...
4
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1answer
362 views

Batch converting .img files to .mgz in FreeSurfer

I have a series of .img files from a previous analysis in SPM that Freesurfer (FS) cannot directly handle. FS comes with a conversion tool, the mri_convert command, but I am not able to make it run ...
4
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0answers
13 views

Do I report all anatomical regions in a large significant cluster identified in functional connectivity seed-to-voxel analysis?

I am conducting a resting-state functional connectivity seed-to-voxel analysis on the 25 participants from the NYC test-retest dataset using the CONN toolbox with the Posterior Cingulate Cortex of the ...
4
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0answers
31 views

Timing accuracy in presentation of videos with different frame rates (with COGENT)

For our fMRI study we want to present videos of 3 seconds duration. The videos have different frame rates: 48 videos were recorded with 50 fps 16 videos were recorded with 25fps 64 videos were ...
4
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0answers
44 views

Library (or manual creation) of ERP components

I'm looking to test some computational models using ERP components as inputs (eg. p300, n170) I'm wondering if there is an existing library anywhere that would have a bank of wave/component examples ...
4
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0answers
433 views

Steady State Topography and Advertising/Preference: Weaknesses? Criticism?

Steady-state topography is a derivation of EEG/ERPs using an evoked potential to an ongoing oscillating stimuli called the steady state visually evoked potential (SSVEP). Variations in the phase ...
3
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1answer
65 views

Why the brain region with less activity is not more responsible for some action?

From my naive understanding, it seems that when people try to find correlations between a human action and a certain pattern of activity in the brain, they measure the brain activity with some device ...
3
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1answer
76 views

Voltage sensitive dyes technique: What is the underlying measure?

I just discovered voltage sensitive dyes technique: I have seen that figures are labelled with dF/F0, what does it stands for?
3
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1answer
150 views

What are the highest ranked neuroscience journals that use double-blind review process?

In terms of impact factor (for a lack of a better proxy), what are the highest ranked neuroscience journals that use double-blind review process? I would be submitting a paper that combines ...
3
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1answer
61 views

Is sign language handled differently by the brain than spoken laguage?

The human's ability to process language in the abstract is somewhat linked to our ability to both produce and understand sounds (see Broca's area), with that in mind, is Sign Language handled ...
3
votes
1answer
312 views

What is the best way to turn EEG scans in to 3D images?

I'm looking for the best way to turn standard EEG scans into 3D images of activity in the brain over the time of scanning, for example like the Glass Brain images or even connectome-style images. I ...
3
votes
1answer
2k views

How many possible states does a brain have?

Suppose I have a box, inside of which is a light which can be either on or off: it has exactly two states. Suppose I wanted to take some "snapshot" of the state of this device, and store all the ...