Questions tagged [neuroimaging]
For questions about techniques to directly or indirectly image the structure, function, or pharmacology of the brain.
119
questions
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18 views
What is the size limit of molecules entering the intracellular sections of a neuron?
As voltage sensitive organic dyes enter the inside of neurons and quantum dots are seeking to replace these due to their higher quantum yield, I was wondering what the seize limit is, as quantum dot ...
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1answer
23 views
Are there equivalent calcium imaging molecules that fluoresce in the presence of neurotransmitters between axons?
Molecules like GCaMP fluoresce when calcium ions attach to them. I was wondering if this can work with the other neurotransmitters in the brain or compounds that transmit signals outside of neurons.
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1answer
30 views
How close are fluorescent dyes to individual neurons in two photon microscopy?
Considering the minute electrical excitation produced by neural cells needed to excite fluorescent dyes, how close are they to these cells, considering that being too close will disrupt cell processes....
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97 views
Opening an aparc+aseg.nii.gz file programmatically in Python
How do you programmatically in Python open and read segmentation data in an aparc+aseg.nii.gz file programmatically?
Is this correct?
...
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23 views
Is there any maping between the AAL to Brodmann areas (BA)?
I am trying to find any correspondence between BA6 (Premotor cortex) and AAL, but there are no information about it. Is there any equivalence table for Brodmann areas and other related anatomic labels?...
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40 views
Can the administration of self-report measures of craving prompt participants with addiction to experience craving during the experiment?
My research focuses on measuring the neural correlates (through resting-state EEG) pre-post an improvisational music therapy session (MT sessions) in clients with substance misuse.
One of my variable ...
2
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1answer
46 views
Measuring postsynaptic potential vs action potential at axon hillock?
I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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1answer
23 views
"runs" or "sessions" in Structural MRI - Purpose and Implications for Quality Control
I am working on a graduate research project using the ABIDE I and II autism datasets.
MRIQC has been run on these data - and I now must remove participants marked as outliers on 3 specific quality ...
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8 views
What's the proposed mechanism of action of Trigeminal Nerve Stimulation (TNS) for ADHD? (And is there some neuroimaging in support of it?)
Last year the FDA approved the first medical device for ADHD, a Trigeminal Nerve Stimulator, a sort "pacemaker" that is used every night on the head of the patient.
I'm trying find what's ...
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32 views
Has anyone tried using functional near-infrared spectropathy to quantitively measure sodium concentrations in the brain?
Functional near-infrared spectropathy "fNIRS", is a biophysics/medical technique that uses the near-infrared part of the electromagnetic spectrum (around 680nm to 810nm in wavelength) to ...
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15 views
Do I report all anatomical regions in a large significant cluster identified in functional connectivity seed-to-voxel analysis?
I am conducting a resting-state functional connectivity seed-to-voxel analysis on the 25 participants from the NYC test-retest dataset using the CONN toolbox with the Posterior Cingulate Cortex of the ...
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18 views
Choice of reference/mid-slice during SPM slice-timing-correction
I'm trying to figure out the simultaneous-multi-slice (SMS) factor for my MR acquisition, to use during slice-timing correction, in SPM12.
The DICOM header obtained during conversion (with the ...
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22 views
How firing of neurons stimulate reality? [duplicate]
Iam just an enthusiast.When I look for how does our brain works it boils down to firing of neurons in a pattern. I read that all of our thoughts, memory is due to firing of networks of neurons in a ...
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1answer
81 views
Which characteristics of neural activity patterns underlie conscious experience?
Which specific characteristics of neural activity patterns are unique for the cortex and neocortex as the presumed "seat of consciousness" and can only be observed there? Activity patterns having ...
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0answers
21 views
How well is biofeedback understood?
From an answer to the question Research suggesting conscious control over brain region activation? I have learned:
»[S]ubjects become better at up-regulating or down-regulating
activation in ...
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20 views
Functional neuronal units that occupy the same brain region
[Thanks to Bryan Krause's advice, I edited the question.]
Definition: Let two functional units be two sets of neurons, A and B, such that the probability of being connected (synaptically or by ...
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1answer
78 views
What is the brain doing when someone tries to solve a physics or math problem that they can’t make any progress on?
Is their brain actually working or is it day dreaming and not functioning if they’re staring at a physics problem and not capable of making any progress on it?
When a student who can’t come up with ...
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2answers
114 views
Is what psychologists define as subconsciousness proven in neuroscience and can the psychological subconsciousness be visualized by neuroscientists?
We read phrases like
The subconsciousness makes up 90% of our brain.
The subconsciousness makes up 95% of our brain.
The subconsciousness can be influenced by hypnosis.
I have yet to see a study in ...
2
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1answer
43 views
Temporally truncate BOLD data
I'm analyzing some resting-state data and some of the scans are 10 min while others are 7 min. I need to cut the last 3 min off of those with 10 min scans so everyone has 7 min of resting-state data. ...
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1answer
74 views
Find volume of lesion mask
I have drawn a lesion mask using FSLeyes on a T1-weighted image for MS patients. Is there tool to get the lesion volume from the mask?
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210 views
Supplementary Motor Area or Juxtapositional Lobule Cortex
Harvard-Oxford Cortical Structural Atlas now calls the 'Supplementary Motor Area' the 'Juxtapositional Lobule Cortex (formerly Supplementary Motor Cortex)'. I've looked for papers that explain the ...
3
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1answer
59 views
Publicly accessible database for the Autistic brain under MRI and/or fMRI
American neuroscientist James H. Fallon released many of the images of MRIs from diagnosed psychopaths and was able to identify a pattern when compared to the average individual. Is there a database ...
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148 views
Noise ceiling estimate is lower than model prediction in RSA?
I am using representational similarity analyses (RSA) to compare models to some fMRI data. As part of this analysis I have computed noise ceilings for each of my regions of interest (ROIs). What's ...
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2answers
76 views
Does the duration of the epoch of interest in fMRI need to be a multiple of TR?
I am designing an fMRI experiment whereby, for each trial, subjects need to listen to an auditory stimulus (of arbitrary duration), and subsequently give a rating for each stimulus.
I intend to ...
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0answers
26 views
Active Sources Extraction
I am using the LORETA-KEY software for source localization, which gives as an output the current density of each voxel.
No voxel has zero current density, so which method should be used to decide the ...
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0answers
43 views
Relaxing your concepts in meditation
I am using the app Waking up from Sam Harris. A lot of his guided meditations tell you to perceive the world as the raw data of experience, instead of perceiving objects and concepts. To illustrate ...
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1answer
31 views
task-fMRI to determine TMS site (online stimulation with that same task)?
I am planning an experiment whereby rTMS would be administered to subjects while they perform a language task, with the hopes of improving performance on this task as compared to sham stimulation.
...
3
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1answer
64 views
Is sign language handled differently by the brain than spoken laguage?
The human's ability to process language in the abstract is somewhat linked to our ability to both produce and understand sounds (see Broca's area), with that in mind, is Sign Language handled ...
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0answers
31 views
What is the term for mimicking other behaviors? [closed]
Say you see an actor playing someone insane, for the next few hours you feel kind of crazy too, especially if you are tired. You may feel annoyed and overwhelmed and mad for no reason, and kind of ...
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2answers
1k views
How do we know human brain development stops around age 25?
I've heard this stated as a fact more times than I can keep track of, but I haven't been able to find papers that actually demonstrate this. This seems to be the most cited paper on the topic, but it ...
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0answers
15 views
What methods exist for converting channel-wise directed (effective) connectiviy estimates to ROI-wise connectivity estimates?
I am reading up on directed connectivity estimates (e.g. Granger causality, DTF, dDTF) in an attempt to find a method that allows me to appropriately convert channel-wise connectivity estimates into ...
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1answer
1k views
Are scintillating scotomas really caused by cortical spreading depression? If so, how is this known to be true?
I have just read about a visual effect called a scintillating scotoma.
Many variations occur, but scintillating scotoma usually begins as a spot of flickering light near or in the center of the ...
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1answer
388 views
What is the difference between an Atlas and a Parcellation?
I come from a computer science background and am just starting out in the area of analyzing brain imaging data (fMRI predominantly) and while going through some of the literature, I am kind of ...
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0answers
24 views
Can a CT scan have advserse cognitive effects on the brain? [closed]
If the normal Xrays scans, despite the low amount of radiation (equivalent to a few hours of background radiation, can be sufficient to cause a burning sensation, then I wonder if the much higher dose ...
3
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1answer
45 views
What does "they tend within and between classes" mean in 'The Irreducible Mind'?
I am a philosophy student but I'm also interested in philosophy of mind, a field that overlaps issues in psychology and neuroscience these days. This passage is taken from a similar multidisciplinary ...
8
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1answer
823 views
Frissons on demand
Have you ever listened to music and it gives you "chills?" This response is called a "frisson," a french word meaning "to shiver."
When I want to access certain emotional and inspirationally charged ...
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33 views
Timing accuracy in presentation of videos with different frame rates (with COGENT)
For our fMRI study we want to present videos of 3 seconds duration. The videos have different frame rates:
48 videos were recorded with 50 fps
16 videos were recorded with 25fps
64 videos were ...
8
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1answer
652 views
In fMRI analyses, what is the t-test actually comparing?
In a 1st-level fMRI analysis, it is unclear to me what the t-test performed for each voxel is actually comparing. I've seen this being described in one of two different ways:
The t-test estimates how ...
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27 views
Has there been any substantive neuroimaging done to study Gendler's belief/alief distinction?
Tamar Gendler proposed a distinction between the concept of "belief" and "alief", "belief" being the more commonly held, intuitive conception of a certain type of propositional attitude and "alief" ...
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1answer
443 views
Jung's Anima and Neurological Basis in Split-Brain Patients; Left-Persona and Right-Anima
So, having skimmed some studies on split-brain patients, it makes me wonder about the whole "left-brain/right-brain" dichotomy that made its rounds in public perception some time ago.
I'm not sure ...
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0answers
66 views
Is synchronization between the MRI scanner and the stimulus presentation necessary for every trial?
I'm planning an event-related fMRI-experiment to investigate the difference in processing natural and computer-generated facial emotion expressions.
I've seen a lot of studies that synchronize the ...
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0answers
35 views
Compute single patient Z-Scores from atlas anatomical zone
I have one brain image from a single patient. I have a set of normal pateints. Both, single patient and normal patients are normalised to an SPM template and the NMI space.
I also have a brain atlas (...
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107 views
ROI analysis of a Z-Score map [closed]
I have a brain z-score image wich is the result of some test. The image is in the SPM space.
How can I perfrom a ROI analisis of different zones? And obtain some statistics for each place.
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0answers
24 views
(Flavours of) Psychophysiological Interactions
The paper by Fischmeister et al. 2016 (Cortex) analysed fMRI task-related connectivity patterns, for two tasks that relied vs did not rely on recursive reasoning. Namely, they found "increased ...
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0answers
50 views
Task-based vs task-positive networks
Do the terms "task-positive network" and "task-based network" refer to the same thing, such as the Fronto-Parietal Control Network (FPCN), as distinct from the task-negative networks such as the ...
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0answers
25 views
Does MEG measure the sum of neural activity or the maximum?
According to Wikipedia, neurons give a response that generates a readable MEG signal when they are firing in a relatively synchronized manner and their current carrying dendrites/axons are all aligned....
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1answer
400 views
What does 'Mean Diffusivity' tell me about the connectivity of cortical areas?
I am reading an article about changes in thalamic volume and connections in relation to age and I understand that thalamic volume decreases with age. The authors find that mean diffusivity (MD) in ...
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46 views
How to cope with the problem of noise in fMRI?
The sounds and noises that a typical MRI scanner produces are problematic for several reasons:
they give - annoying as they are - a strong feel of uncomfortableness to any subject or patient
they are ...
4
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1answer
406 views
During body-scan ('sweeping') meditation, what does brain-imaging (e.g. fMRI) look like?
I do not know how extensive body scans have been studied with brain-imaging techniques, e.g. fMRI.
Body scan is a meditation technique developed by Jon Kabat-Zinn. It was derived from a meditation ...
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2answers
96 views
Can we identify specific emotions on the basis of fMRI scans?
I am looking for fMRI studies in which the emotional response of a person listening to music is visible in the fMRI scans, paralleled by a retrospective think aloud report of the person describing his/...