Questions tagged [neuroimaging]

For questions about techniques to directly or indirectly image the structure, function, or pharmacology of the brain.

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12 views

What is the size limit of molecules entering the intracellular sections of a neuron?

As voltage sensitive organic dyes enter the inside of neurons and quantum dots are seeking to replace these due to their higher quantum yield, I was wondering what the seize limit is, as quantum dot ...
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1answer
21 views

Are there equivalent calcium imaging molecules that fluoresce in the presence of neurotransmitters between axons?

Molecules like GCaMP fluoresce when calcium ions attach to them. I was wondering if this can work with the other neurotransmitters in the brain or compounds that transmit signals outside of neurons.
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How close are fluorescent dyes to individual neurons in two photon microscopy?

Considering the minute electrical excitation produced by neural cells needed to excite fluorescent dyes, how close are they to these cells, considering that being too close will disrupt cell processes....
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85 views

Opening an aparc+aseg.nii.gz file programmatically in Python

How do you programmatically in Python open and read segmentation data in an aparc+aseg.nii.gz file programmatically? Is this correct? ...
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Is there any maping between the AAL to Brodmann areas (BA)?

I am trying to find any correspondence between BA6 (Premotor cortex) and AAL, but there are no information about it. Is there any equivalence table for Brodmann areas and other related anatomic labels?...
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Can the administration of self-report measures of craving prompt participants with addiction to experience craving during the experiment?

My research focuses on measuring the neural correlates (through resting-state EEG) pre-post an improvisational music therapy session (MT sessions) in clients with substance misuse. One of my variable ...
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1answer
40 views

Measuring postsynaptic potential vs action potential at axon hillock?

I have been reading literature regarding Neuronal potential measurement. Conventionally, researchers use electrode-based method to measure action potential. However, as it's of high invasiveness and ...
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1answer
15 views

“runs” or “sessions” in Structural MRI - Purpose and Implications for Quality Control

I am working on a graduate research project using the ABIDE I and II autism datasets. MRIQC has been run on these data - and I now must remove participants marked as outliers on 3 specific quality ...
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What's the proposed mechanism of action of Trigeminal Nerve Stimulation (TNS) for ADHD? (And is there some neuroimaging in support of it?)

Last year the FDA approved the first medical device for ADHD, a Trigeminal Nerve Stimulator, a sort "pacemaker" that is used every night on the head of the patient. I'm trying find what's ...
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26 views

Has anyone tried using functional near-infrared spectropathy to quantitively measure sodium concentrations in the brain?

Functional near-infrared spectropathy "fNIRS", is a biophysics/medical technique that uses the near-infrared part of the electromagnetic spectrum (around 680nm to 810nm in wavelength) to ...
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14 views

Do I report all anatomical regions in a large significant cluster identified in functional connectivity seed-to-voxel analysis?

I am conducting a resting-state functional connectivity seed-to-voxel analysis on the 25 participants from the NYC test-retest dataset using the CONN toolbox with the Posterior Cingulate Cortex of the ...
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Choice of reference/mid-slice during SPM slice-timing-correction

I'm trying to figure out the simultaneous-multi-slice (SMS) factor for my MR acquisition, to use during slice-timing correction, in SPM12. The DICOM header obtained during conversion (with the ...
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22 views

How firing of neurons stimulate reality? [duplicate]

Iam just an enthusiast.When I look for how does our brain works it boils down to firing of neurons in a pattern. I read that all of our thoughts, memory is due to firing of networks of neurons in a ...
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79 views

Which characteristics of neural activity patterns underlie conscious experience?

Which specific characteristics of neural activity patterns are unique for the cortex and neocortex as the presumed "seat of consciousness" and can only be observed there? Activity patterns having ...
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21 views

How well is biofeedback understood?

From an answer to the question Research suggesting conscious control over brain region activation? I have learned: »[S]ubjects become better at up-regulating or down-regulating activation in ...
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20 views

Functional neuronal units that occupy the same brain region

[Thanks to Bryan Krause's advice, I edited the question.] Definition: Let two functional units be two sets of neurons, A and B, such that the probability of being connected (synaptically or by ...
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66 views

What is the brain doing when someone tries to solve a physics or math problem that they can’t make any progress on?

Is their brain actually working or is it day dreaming and not functioning if they’re staring at a physics problem and not capable of making any progress on it? When a student who can’t come up with ...
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110 views

Is what psychologists define as subconsciousness proven in neuroscience and can the psychological subconsciousness be visualized by neuroscientists?

We read phrases like The subconsciousness makes up 90% of our brain. The subconsciousness makes up 95% of our brain. The subconsciousness can be influenced by hypnosis. I have yet to see a study in ...
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42 views

Temporally truncate BOLD data

I'm analyzing some resting-state data and some of the scans are 10 min while others are 7 min. I need to cut the last 3 min off of those with 10 min scans so everyone has 7 min of resting-state data. ...
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64 views

Find volume of lesion mask

I have drawn a lesion mask using FSLeyes on a T1-weighted image for MS patients. Is there tool to get the lesion volume from the mask?
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191 views

Supplementary Motor Area or Juxtapositional Lobule Cortex

Harvard-Oxford Cortical Structural Atlas now calls the 'Supplementary Motor Area' the 'Juxtapositional Lobule Cortex (formerly Supplementary Motor Cortex)'. I've looked for papers that explain the ...
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1answer
59 views

Publicly accessible database for the Autistic brain under MRI and/or fMRI

American neuroscientist James H. Fallon released many of the images of MRIs from diagnosed psychopaths and was able to identify a pattern when compared to the average individual. Is there a database ...
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126 views

Noise ceiling estimate is lower than model prediction in RSA?

I am using representational similarity analyses (RSA) to compare models to some fMRI data. As part of this analysis I have computed noise ceilings for each of my regions of interest (ROIs). What's ...
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59 views

Does the duration of the epoch of interest in fMRI need to be a multiple of TR?

I am designing an fMRI experiment whereby, for each trial, subjects need to listen to an auditory stimulus (of arbitrary duration), and subsequently give a rating for each stimulus. I intend to ...
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26 views

Active Sources Extraction

I am using the LORETA-KEY software for source localization, which gives as an output the current density of each voxel. No voxel has zero current density, so which method should be used to decide the ...
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43 views

Relaxing your concepts in meditation

I am using the app Waking up from Sam Harris. A lot of his guided meditations tell you to perceive the world as the raw data of experience, instead of perceiving objects and concepts. To illustrate ...
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1answer
29 views

task-fMRI to determine TMS site (online stimulation with that same task)?

I am planning an experiment whereby rTMS would be administered to subjects while they perform a language task, with the hopes of improving performance on this task as compared to sham stimulation. ...
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1answer
61 views

Is sign language handled differently by the brain than spoken laguage?

The human's ability to process language in the abstract is somewhat linked to our ability to both produce and understand sounds (see Broca's area), with that in mind, is Sign Language handled ...
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31 views

What is the term for mimicking other behaviors? [closed]

Say you see an actor playing someone insane, for the next few hours you feel kind of crazy too, especially if you are tired. You may feel annoyed and overwhelmed and mad for no reason, and kind of ...
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1k views

How do we know human brain development stops around age 25?

I've heard this stated as a fact more times than I can keep track of, but I haven't been able to find papers that actually demonstrate this. This seems to be the most cited paper on the topic, but it ...
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15 views

What methods exist for converting channel-wise directed (effective) connectiviy estimates to ROI-wise connectivity estimates?

I am reading up on directed connectivity estimates (e.g. Granger causality, DTF, dDTF) in an attempt to find a method that allows me to appropriately convert channel-wise connectivity estimates into ...
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1answer
1k views

Are scintillating scotomas really caused by cortical spreading depression? If so, how is this known to be true?

I have just read about a visual effect called a scintillating scotoma. Many variations occur, but scintillating scotoma usually begins as a spot of flickering light near or in the center of the ...
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1answer
349 views

What is the difference between an Atlas and a Parcellation?

I come from a computer science background and am just starting out in the area of analyzing brain imaging data (fMRI predominantly) and while going through some of the literature, I am kind of ...
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24 views

Can a CT scan have advserse cognitive effects on the brain? [closed]

If the normal Xrays scans, despite the low amount of radiation (equivalent to a few hours of background radiation, can be sufficient to cause a burning sensation, then I wonder if the much higher dose ...
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44 views

What does “they tend within and between classes” mean in 'The Irreducible Mind'?

I am a philosophy student but I'm also interested in philosophy of mind, a field that overlaps issues in psychology and neuroscience these days. This passage is taken from a similar multidisciplinary ...
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768 views

Frissons on demand

Have you ever listened to music and it gives you "chills?" This response is called a "frisson," a french word meaning "to shiver." When I want to access certain emotional and inspirationally charged ...
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31 views

Timing accuracy in presentation of videos with different frame rates (with COGENT)

For our fMRI study we want to present videos of 3 seconds duration. The videos have different frame rates: 48 videos were recorded with 50 fps 16 videos were recorded with 25fps 64 videos were ...
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1answer
572 views

In fMRI analyses, what is the t-test actually comparing?

In a 1st-level fMRI analysis, it is unclear to me what the t-test performed for each voxel is actually comparing. I've seen this being described in one of two different ways: The t-test estimates how ...
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23 views

Has there been any substantive neuroimaging done to study Gendler's belief/alief distinction?

Tamar Gendler proposed a distinction between the concept of "belief" and "alief", "belief" being the more commonly held, intuitive conception of a certain type of propositional attitude and "alief" ...
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1answer
409 views

Jung's Anima and Neurological Basis in Split-Brain Patients; Left-Persona and Right-Anima

So, having skimmed some studies on split-brain patients, it makes me wonder about the whole "left-brain/right-brain" dichotomy that made its rounds in public perception some time ago. I'm not sure ...
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64 views

Is synchronization between the MRI scanner and the stimulus presentation necessary for every trial?

I'm planning an event-related fMRI-experiment to investigate the difference in processing natural and computer-generated facial emotion expressions. I've seen a lot of studies that synchronize the ...
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35 views

Compute single patient Z-Scores from atlas anatomical zone

I have one brain image from a single patient. I have a set of normal pateints. Both, single patient and normal patients are normalised to an SPM template and the NMI space. I also have a brain atlas (...
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107 views

ROI analysis of a Z-Score map [closed]

I have a brain z-score image wich is the result of some test. The image is in the SPM space. How can I perfrom a ROI analisis of different zones? And obtain some statistics for each place.
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(Flavours of) Psychophysiological Interactions

The paper by Fischmeister et al. 2016 (Cortex) analysed fMRI task-related connectivity patterns, for two tasks that relied vs did not rely on recursive reasoning. Namely, they found "increased ...
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50 views

Task-based vs task-positive networks

Do the terms "task-positive network" and "task-based network" refer to the same thing, such as the Fronto-Parietal Control Network (FPCN), as distinct from the task-negative networks such as the ...
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25 views

Does MEG measure the sum of neural activity or the maximum?

According to Wikipedia, neurons give a response that generates a readable MEG signal when they are firing in a relatively synchronized manner and their current carrying dendrites/axons are all aligned....
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388 views

What does 'Mean Diffusivity' tell me about the connectivity of cortical areas?

I am reading an article about changes in thalamic volume and connections in relation to age and I understand that thalamic volume decreases with age. The authors find that mean diffusivity (MD) in ...
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46 views

How to cope with the problem of noise in fMRI?

The sounds and noises that a typical MRI scanner produces are problematic for several reasons: they give - annoying as they are - a strong feel of uncomfortableness to any subject or patient they are ...
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386 views

During body-scan ('sweeping') meditation, what does brain-imaging (e.g. fMRI) look like?

I do not know how extensive body scans have been studied with brain-imaging techniques, e.g. fMRI. Body scan is a meditation technique developed by Jon Kabat-Zinn. It was derived from a meditation ...
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95 views

Can we identify specific emotions on the basis of fMRI scans?

I am looking for fMRI studies in which the emotional response of a person listening to music is visible in the fMRI scans, paralleled by a retrospective think aloud report of the person describing his/...