Questions tagged [ltp]

For questions relating to long term potentiation (LTP), the process of priming brain cells to improve synaptic efficacy.

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How convincing is the evidence that LTP underlies memory formation?

(Yeah, I'm aware this question probably is rather close to being opinion based, but I'll ask anyway.) A (widely cited) 2004 review by Lynch was somewhat reserved on the topic, noting that some ...
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50 views

Does NMDA-receptor activation depend on neighboring AMPA-receptor activity?

This question is coming out of a couple points of confusion after I learned about about NMDA receptors' role in LTP. I got the impression that after AMPA receptors were activated enough, which ...
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How does the human brain store motor skills for long term?

The way I understand it, memory goes through calcium influx induced LTP (Long Term potentiation) for short term storage. Long term storage requires protein synthesis. (#1). However, a meta-analysis (#...
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60 views

How does the timing work out for dopamine to affect the development of long-term potentiation?

I just recently learned (indirectly from this source) that long-term potentiation/depression only takes place when you have large/small amounts of dopamine present at the relevant synapse. However, my ...
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What can be inferred about the strength of the synapse from an electron microscope image?

In the following EM image (1um scale), there are several synapses: Image or HD Version What information about the synaptic strengths can be extracted from this image? Does vesicle count contain ...
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Is the process of long term potentiation (LTP) definitively linked with brain plasticity?

Given that the process of Long Term Potentiation (LTP) is one of the processes that increases synaptic efficacy: Is it reasonable to conclude that the process of LTP is sufficient and necessary to ...