Questions tagged [experimental-neuroscience]
For practical questions about performing neuroscience experiments.
28 questions
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How does one add a commutator to the UCLA miniscope cable?
The UCLA miniscope is an open source alternative to the Inscopix system for calcium imaging in freely behaving animals. One of the benefits of their system that they tout is the ability to have a ...
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How to stain for orexin neurons in mice?
I am interested in studying possible depletion of orexin levels in the brains of some mice, and am wondering if anyone knows of a staining substance/technique for use on slices of fixed mouse brains ...
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Simultaneous extracellular recording from different distant sites (in rodents)
I wonder whether it is technically possible today to have simultaneous extracellular recording in awake rodents (e.g., mice) from different non-proximate sites (e.g., V1 and frontal cortex). I mean to ...
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At what impedances should one gold plate 12.5-µm diameter nichrome wire tetrodes for targeting different brain areas?
Extracellular electrophysiological recordings of rodent brains using tetrodes requires plating them with gold solution in order to achieve appropriate impedances.
How does the ideal plating ...
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Does the peripheral nervous system processes information like central neurons do?
Neural coding deals with the problem on how neurons or a network of neurons processes a stimulus and creates a response in form of electrical action potentials. Information then might be encoded in ...
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Converting human's memory into digital data
I am wondering whether converting someone's memory into digital data is possible or not. It may sound ridiculous. However, if chance is not 0 then what kind of studies might be used? What kind of ...
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How does acute tryptophan depletion work?
The literature online about this practice is very poor. The theory goes like this:
A mix of amino acids that does not include tryptophan will lower the proportion of tryptophan in the bloodstream.
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Where can I find the connectivity matrix of the connectome of C. Elegans?
I am trying to find the entire connectivity matrix for the connectome of the roundworm C. elegans. It is a much studied animal, as it features just a handful of neurons in its nervous system, 302 to ...
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How to record mouse-pointer fixations? [closed]
I'm planning an experiment in which participants will respond to a stimulus by using a mouse to click somewhere on a computer screen. I'm interested in analyzing the strategies participants use to ...
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Facing problem while connecting OpenViBE Acquisition Server with Python
I am trying to connect OpenViBE Acquisition Server with Python (without using OpenViBE Driver). I read the OpenViBE documentation (http://openvibe.inria.fr/how-to-use-labstreaminglayer-in-openvibe/) ...
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Is anyone here familiar with techniques and/or equipment for performing cerebrospinal fluid transfusions?
I am a student at a University and we are discussing putting together a lab assessing the benefits that may be associated with cerebrospinal fluid (CSF) transfusions in Alzheimer's disease mice. So ...
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What would be areas of ethical or safety concerns with a smartphone app interacting with people sleeping?
The BBC News article Hi-tech dreamcatcher defeats sleep amnesia mentions a recent talk by Adam Haar Horowitz and then describes some limited tests of an apparatus called Dormio at the MIT media lab, ...
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Differences in reaction time on visual tasks with and without binocular disparity ques?
Have there been any studies done that test the reaction time to vision processing tasks with and without the benefit of binocular disparities? I have been wondering how much depth information (such as ...
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Constraints on dataset size for AI-assisted connectome reconstruction
From an exchange with Dr. Seung, an expert on connectomics, I learned that one of his former PhD students Viren Jain is leading the Connectomic effort at Google using supervised learning methods. Now, ...
user3503
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experimental tracking and treating bipolar disorder
Is there a way to measure what neurotransmitters (and in what amount) are present in a person via blood or other method? I feel like if such information was available there could be experiments ...
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What is the role of mesolimbic dopamine in associative or reinforcement learning?
I was recently told about a Science paper that suggests the old model of association of cause with effect is incorrect. In this model, cue comes, reward occurs, cue comes again, prediction of reward ...
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Are neural sensitivity tests used in proving/refuting Freudian and Neo-Freudian theories?
Given that Freudian theories root their explanatory models in neurology (that is, selected extra-sensitive (erogenous) body zones), has any scientific study tried to prove/refute them, by measuring ...
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System 1 (fast and unconscious) thinking
Can you please recommend some literature about experiments used to study system 1 (fast and unconscious) decision making (Kahneman, 2011) in human or non-human animals?
Reference
Kahneman, D. (2011). ...
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Are skull screws required for stable implants
I'm wondering if there is any quantitative (or a least first-hand qualitative) evidence that relates the stability of chronic, invasive neural recordings with the use of skull screws versus a high-...
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Good neuroscience research blogs
In the field of AI research there are really good research blogs that regularly analyse methods and review papers. Examples that come to mind are:
BAIR blog: The Berkeley AI Research blog
Distill: an ...
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Why do we understand so little about the brain? [closed]
Most of the things our brain does we have no clue how it does it. Thought, Memory storage and recall, dreaming, spatial awareness, timekeeping, emotions, pain and the big ONE- qualia. We have no clue ...
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How to determine nerve conduction velocity?
Can anyone suggest good sources or papers to understand about experimental setup and procedure for measuring nerve conduction velocity for various types of neurons?
I wish to learn how such ...
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Mismatch negativity vs. mismatch response
MMN x MMR - mismatch negativity versus mismatch response:
How are the concepts related and what is the difference between them?
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Which possible methods can be used to determine if a certain part of the brain is active?
The question goes back to this tweet:
Julia @JuliaHass
I just learned that elephants think humans are cute the way humans think puppies are cute (the same part of the brain lights up when they see ...
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Any neuroscience related intelligence theories?
Correlations between biological measurements and intelligence has been made in the past, e.g. blood flow or metrics like cortex size, though are there any specific neuroscience related intelligence ...
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How close an electrode should be to the target neural tissue? [closed]
Intracortical electrodes are used to record neural signals. How close an electrode should be to the target neural tissue to obtain sufficiently clean / usable or hi-fidelity signal?
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In an experiment with animated stimuli, should I accept answers during Animation Time and count it into the Response Time?
In an experimental task where the response time is an important variable to compare two groups with different conditions, and there are animated stimuli (movement), should the response be accepted ...
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Can a brain dead person be revived through a modified defribillator?
Is the analogy of a defribillator for a brain be able to tackle brain deaths ? What are the limitations to this idea?
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