Questions tagged [dopamine]
Questions about neurotransmitter dopamine or 3,4-dihydroxyphenethylamine. Dopamine production, deficiency and drug interaction and illnesses affected by or effecting dopamine levels.
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Why do antipsychotics bind to D2-like instead of D1-like receptors?
My understanding is that:
The dopamine hypothesis of schizophrenia states that the positive symptoms are a result of excessive neurotransmission of dopamine in the mesolimbic pathway.
D1-like ...
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Does temporal difference prediction error decrease as it back-propagates towards CS in simple Pavlovian conditioning?
I've been working on a simulation of value and prediction error change according to the temporal difference model during Pavlovian trace conditioning in R and I've been getting some unexpected outputs ...
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Benefits of Preserving Dopamine
I recently came across a short piece on Twitter advocating for the preservation of dopamine release. The writer stated that a list of things should be avoided to preserve dopamine.
Preserve your ...
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Why might sleeping on the floor alleviate PTSD symptoms?
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Does sleeping on the floor have similar neurotransmitter effects, as sleeping under a weighted blanket might? Psychiatrically, would it be expected that a person having PTSD would find ...
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How does THC tolerance work and how does this impact psychotic effects of THC?
I am interested in knowledge about the inner workings of THC tolerance.
I have no direct sources, but know several (n = 7) individuals who say they build up a tolerance at chronic consumption and lose ...
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Does AD(H)D increase the risk of (drug induced) psychosis?
I read that patients with ADD can exhibit a hypersensitivity of dopamine in the mesolimbic area and a hyposensitivity of dopamine in the prefrontal cortex which makes them more susceptible to ...
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Would it be possible to directly block dopamine release in the mesolimbic area?
Thinking about the treatment of (drug induced) psychosis I'm having the following thoughts.
Drug induced psychosis makes up for 25% - 50% of cases of patients experiencing psychosis . Nevertheless ...
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Does dopamine suppress serotonin production?
In a youtube video in spanish, I heard that dopamine suppress serotonin production. Is that true?
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What does the brain release in anticipation of a rewards besides dopamine?
Dopamine is released in anticipation of a reward. Does the brain release other neurotransmitters besides dopamine in anticipation of a reward?
I'm wondering if the mere thought of a reward will ...
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Is there a name or any research on white flashing behind the eyes?
I have encountered anecdotal evidence that sometimes when people meditate, as they progress to higher levels, they sometimes experience flashing white light behind the eyes. And I have also ...
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How can someone enjoy something without dopamine?
In this video, Andrew Huberman says people and even animals with depleted dopamine levels can still enjoy stuff.
How does one enjoy without dopamine? Isn't it the pleasure chemical?
Can serotonin, ...
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how dopamine levels are related with psychosis and schizophrenia?
can someone explain me what is the role of dopamine in psychosis and schizophrenia. somewhere on the internet i read that low dopamine is associated with diseases like psychosis and schizophrenia. And ...
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Does dopamine detox work?
There are lot of videos on youtube like this which talk about dopamine detox for a week, month or so. Does it actually work? Don't we get distracted anymore or get less distracted? Is it necessary to ...
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What are the pharmacodynamics (Ki nM) of the monoamine neurotransmitters?
Ok, so any psychoactive drug will have different affinities for different receptor types. For instance, sertraline has an extreme affinity for the SERT and very little affinity for the 5-HT1A receptor....
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Why does a human mind repeat the same mistakes? [closed]
Why does a person go on repeating the same mistakes again and again even if he does not want to? He knows that he is going to regret it later since he has already repeated this several times in the ...
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Why studying is difficult than playing games and watching movies, social media etc?
I am aware of dopamine and I often watch videos related to this. My question is why studying is difficult but watching social media and movies seem easy.
if it is about novelty that "When we ...
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At what point do dopamine/serotonin receptors become downregulated/upregulated?
It's well known that behaviors like pornography viewing lead to dopamine receptor downregulation to compensate for the extreme stimulation. Obviously, drugs like methamphetamine would lead to an even ...
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Why actual happy experiences don't have some side effects like stimulant drugs?
Science says that the mental side effects of stimulant drugs, like depression, are caused due to the overload of dopaminergic activity in the brain, but when people experience actual great things the ...
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Are food rewards a good long term learning strategy?
This could be a question for parenting SE, but I am looking to understand the mechanism, so I am looking for a core answer from a psychological perspective; without all of the cultural noise that ...
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If stimulus triggers dopamine release, can dopamine release trigger memory recall of stimulus?
Modern science of sleep is starting to lean towards a viewpoint that dopamine has an important function in dreaming, and that dopaminergic pathways - mesolimbic and mesocortical are activated during ...
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Dopamine is released in anticipation. What chemial is released when the reward is actually recieved and complete the feedback loop?
The figure shows Twice as much dopamine was released when there is a 50/50 chance of getting the reward vs 100%.
So brain releases dopamine in anticipation of reward. But how does the brain confirm ...
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What determines whether a monoamine neurotransmitter is recycled or broken down by MAO?
When a neurotransmitter detaches from the receptor and is returned to the neuron via the transporter, what are the primary factors that influence whether that molecule is re-stored in a vesicle by ...
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What is the actual work of dopamine? Does it provide happiness or gives birth to desire?
As per my initial readings about dopamine are concerned it is usually stated that (like here )
Dopamine is a hormone associated with happiness.
But today I have come across a video in which the ...
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Can we change a particular addiction into another addiction?
My current knowledge about dopamine and serotonin came from a series of articles and web pages, a few videos also.
As per my knowledge and readings I know that addiction is about reward, a person’s ...
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Beyond CBT and MBI, what are effective behavioral interventions for modern lifestyle addictions during their engagement?
Some modern activities exploit the primitive mammalian reward areas in the brain. They include immediate access to social media, video games, music, sugar, pornographic material, gambling etc. Worse, ...
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Social Media and General Addiction [closed]
I have a question made of four aspects on addiction and dopamine neurobiology.
1. I'm currently wondering whether the addictive potential of social media can be quantified. I'm aware it probably ...
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What introductory textbook is available about the corticostriatal brain circuitry?
I want to understand the basal ganglia better. In particular, I want to understand the role of the corticostriatal brain circuitry for non-motor functions, including emotion and cognition.
I have ...
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Facebook dopamine kick - any proof?
A lot of people are writing that Facebook and other social media sites cause users to be addicted by serving up well timed dopamine kicks in response to interactions. I was searching for any sort of ...
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Why brain can't get used to low dopamine levels? [closed]
When you use dopamine increasing drugs (such as cocaine) for long time the brain down-regulates dopamine receptors.Then dopamine has less sites to bind, therefore not making the same effect as before, ...
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What causes passion, psychologically and chemically, and how does it last? [closed]
I recently finished reading "Habits of a happy brain", which discusses the role of oxytocin, serotonin, endorphin, dopamine, and cortisol in seeking behavior.
The book argues that we evolved to ...
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Psychological theories about the end of a romantic relationship
There's no doubt: many couples break and many marriages break, what happens in these cases?
In the loving encounter brain areas aimed at judgment and critical analysis, are clouded by an increase of ...
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How does timing of pleasure / dopamine / reward influence the formation of positive association? [closed]
Suppose the following idealized experiment:
Setup:
A pill/medication which simply induces pleasure. Perhaps something like a perfect dopamine antagonist with no side-effects. Call it P
A task which ...
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Does dopamine signal become stronger when goal distance is defined using time?
Howe et al (2013) found that a dopamine signal becomes stronger as a goal is approached. The experiment involved rats running in a maze. If the rats were close to solving the maze, the dopamine signal ...
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What's the relation between firing of dopaminergic neurons and dopamine dispersion in terms of neurophysiological processes?
Question: How does the firing of dopaminergic neurons affect the dispersal of dopamine?
Evidence of my limited familiarity with dopaminergic neurons and motivation for asking the question:
Most of ...
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Are there any ways to increase dopamine and serotonin levels when working or learning something complex?
There is much information regarding learning styles and ways to leverage them, along with boosting focus, alertness and concentration.
However, I'm looking for accompanying information that would be ...
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Is gaming more addictive than watching movies or tv shows?
Are there studies that demonstrate that gaming is more addictive than watching movies or tv shows?
There's this article that talks about dopamine and rewards. It makes sense, but are there similar ...
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How does excess of dopamine affect one's mental health?
If a person takes dopamine increasing medication for some illness, what effect will it have on his/her mental health considering that medication doesn't target just one area of the brain ?
In ...
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What is the relationship between dopamine and mathematical ability (if any)?
I am curious to know if there is any existing literature that suggests that an increase in dopamine lends itself to an increased interest in solving problems of a mathematical nature.
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How does Parkinson's disease result in tremors?
From what I understand, Parkinson's disease is caused by the death of dopamine producing cells in the substantia nigra, however I don't understand how that causses the symptoms of Parkinson's. I am ...
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How does the timing work out for dopamine to affect the development of long-term potentiation?
I just recently learned (indirectly from this source) that long-term potentiation/depression only takes place when you have large/small amounts of dopamine present at the relevant synapse. However, my ...
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