Questions tagged [depression]

For questions regarding depressed mood, whether in healthy individuals or those for which the condition manifests as a disorder.

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35 views

How to offer support to an American acquaintance with depression?

So, an online acquaintance of mine has mentioned that they're suffering from severe depression recently, and my natural response is to want to offer them support and encouragement - maybe suggest that ...
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Why do monoamine oxidase enzymes increase in the brain as we age?

What's behind the natural increase of monoamine oxidase enzymes production with age? And other than taking MAOI is there another way to reduce their activity, i.e reduce their endogenous production?
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Using Vagus Nerve Stimulation to treat Depression

I came across an article written recently concerning the use of Vagus Nerve Stimulation (VNS) to treat difficult-to-treat depression (DTD) and other mood disorders (Sackeim, et al. 2020). However, ...
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Are some latitudes or climates more conducive to human happiness than others?

Background The 19th century Chinese political philosopher and dissident Kang Youwei wrote that among the more severe miseries of this life are: premature death, mutilation, slavery, and living outside ...
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Any studies that assess effects of treatment to individual depression symptoms

As an study/research idea, I have been going through articles about treatment response (mostly SSRI and other antidepressants) related to treating depression, but many studies seem to be mostly ...
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Severe depression VS Schizophrenia

One of interesting things in severe depression is psychosis and how it happens that such conditions occur and what is the difference between this type of psychosis and specific conditions of ...
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127 views

Can people fake mental illness to gain sympathy?

In the last decade, a lot of famous personalities and celebrities have opened up about suffering from mental disorders, largely depression. This has caused the younger generation to accept and seek ...
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What has changed in your brain after electroconvulsive “therapy” (ECT)?

From this Wikipedia article: Electroconvulsive therapy (ECT), formerly known as electroshock therapy, is a psychiatric treatment in which seizures in the brain (without muscular convulsions) are ...
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Asking “What's wrong in you life?” → Person sees more problems

I think if you ask a person "What's wrong in your life?" several times (for example monthly) the person starts to focus on negative things. Maybe questions like this can have a negative ...
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Explanation of anti-depressive effect of newer antipsychotics

In my understanding, many newer antipsychotics (e.g. olanzapine and quetiapine) are considered to have an anti-depressive effect. Olanzapine: For olanzapine I found this on wikipedia: "it [...
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Why does suicide risk increase just after starting an antidepressant?

There are many ways of treating depression, one of which is administering antidepressants. From this site, and several others, I read that risk of suicide increases after starting an antidepressant. ...
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What is the approximate average duration of a SCID-5 interview for diagnosing winter depression?

What is the approximate average duration of a DSM-V structured clinical interview for diagnosing winter depression? I would be very grateful for the answer!
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Causality regarding neurotransmitter imbalance and depression

Neurotransmitter imbalances are blamed for various psychiatric conditions (depression, ADHD, etc). Clearly plasma levels of neurotransmitters are confirmed to be abnormal in some people with such ...
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What can happen if a human takes SB-243213?

SB-243213 acts as a selective inverse agonist for the 5-HT2C receptor. The 5-HT2C receptor is one of many 5-HT receptors which are receptors that bind serotonin, and seems to play a major role in ...
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Reducing smoking and mental health benefits

Recently I noticed improved mental health (better mood, better cognition? more energy) after reducing smoking.Is it backed up by research? I know stopping smoking is, but reducing? http://www....
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why we failed to convince our own mind by reasoning and rational arguments over mental illness like depression, anxiety, phobia?

For example, one of my friend has fear of heights, even if there is a strong glass window and no reason for him to fall off. He is even aware and admits his fear is irrational. Many may say it’s in ...
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Triptans and SSRIs

When talking about triptans used for migraines such as Zolimitriptan, such drugs are selective serotonin receptor agonists. SSRIs, as their function states, are Selective Serotonin Reuptake ...
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113 views

How much ashwagandha to relieve depression?

I've read this article, where is the herb ashwagandha which could treat depression. Particularly: In one controlled 60-day study in 64 stressed adults, those ...
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Is depression part of who a person is? [closed]

I have been diagnosed with major depressive disorder, commonly known as depression. Some days ago I had a discussion with my therapist about whether or not depression is part of the person I am. She ...
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Neuralink in depression treatment

In this article there is a statement that Neuralink can help people with Parkinson’s disease, epilepsy, and depression by promptly sending electric pulses into the areas responsible for their ...
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112 views

Does belief in an afterlife play a role in suicide rates?

Religious beliefs, in particular views on the afterlife, could plausibly influence suicide. Is there some study which tries to look at how belief systems play a role in the number of suicides in some ...
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Recovery of memory especially working memory after depression

The impact of depression on memory and working memory has been discussed extensively in the thread below. I can't seem to find information about rehabilitation and recovery of memory after depression....
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Post alcoholic depression and mental health

We all might have experienced a post-alcoholic hangover after heavy drinking. I think this includes a depressive state, which doesn't last long and wears off once we take rest. My question is whether ...
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How strong is the evidence for the effectiveness of psychoanalysis in the treatment of depression?

I often hear claims that psychoanalysis is ineffective, takes too long, is just pseudo-science, that other therapies such as cognitive-behavioural should be preferred or even that it should be ...
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What is the meaning of behaviorally oriented outside-in nature of therapy?

What is the meaning of behaviorally oriented outside-in nature of therapy? I am especially interested why this outside-in word was used but please provide me a wider context of this type of therapy. ...
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Do psychiatrists and researchers themselves don't have an idea how antidepressants work?

This question may be seen as an extension of my previous question, here. I was talking to a person online where s/he mentioned that psychiatrists themselves don't have an idea as to how SSRIs work. ...
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Does amnesia cure depression?

If someone has a miserable childhood and has Dysthymia, but then they suffer from amnesia and forget everything, are they cured of their depression?
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How does psychiatry judge suicide by military and political leaders?

Peru's ex-president Garcia's suicide to avoid arrest reminded me of general officers and politicians who, although wicked, were foxy but rational. They ought've been punished, but they cunningly ...
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What are some examples of psychosis in people who have major depression?

What are some examples of psychosis in people who have major depression? Especially how do delusions show up? "Experiencing psychosis can be frightening and confusing, and psychosis can present ...
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Are there ways to accelerate the recovery from depression via novel pharmacological antidepressants?

Are there any scientists making substantial progress in the development of far more effective antidepressants? Are there any groups of people interested in developing antidepressants based on genetic ...
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Ritalin for treating attention and lack of focus in depression

I’d like to know if there’s research about the use of ritalin for treating attention deficit in Major Depression Disorder.
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How does a person know if he should seek treatment for depression since feeling moody is unavoidable?

Life is not a bed of roses. All of us feel moody sometimes due to failures in life. This is perfectly normal. However, depression is abnormal. How does a person know if he needs to seek treatment for ...
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Is 'your mom will be sad' actually a good argument to pose to someone thinking of committing suicide?

I often come across people pointing out that the close relatives of someone who is thinking about committing suicide will grieve, as an argument against doing it. However, I've noticed that it is ...
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How do serotonin antagonist and reuptake inhibitors work as an antidepressant?

The monoamine hypothesis postulates that the deficit of certain neurotransmitters is responsible for depression, and even that certain neurotransmitters are linked to specific symptoms. If suppose ...
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Why does venlafaxine have lower incidence of sexual dysfunctions at higher doses?

Venlafaxine at low dosages strongly inhibits serotonin, at moderate dosages also norepinephrine and only high dosages it also inhibits dopamine. The ratio is the following. serotonin : ...
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Is it reasonable to leave a therapy session feeling worse? [closed]

I apologize for (possibly) violating the only rule that shows up when you're about to ask a question: ask questions that can be answered rather than discussed. But I'm hoping this question might ...
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198 views

Can listening to sad songs lead to depression?

When we listen to a sad song, we may experience sadness ourselves. Can this sadness lead to depression?
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What is a “psychological evaluation” for kids?

What does a psychological evaluation consist of for pre-teens and adolescents? I work with a child who has been abused (physically and emotionally) who is having suicidal ideations with one parent, ...
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Which mental illnesses are probably natural? [closed]

Which states of mind that are classified as mental illnesses might be a natural and useful part of our brains? For example, some evolutionary biologists have suggested that some types of depression ...
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268 views

Depression Causing Body Dysmorphic Disorder (BDD)

Whilst trying to think of non-chemical/hormonal causes of low self-esteem when reading Is low self-esteem, a brain chemical imbalance problem, rather than a personality defect, and can't be fixed ...
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776 views

Use of Botulinum toxin A (botox) to treat depression and its effect on fight/flight repsonse

Over in Health.SE, @faustus provided a couple of references to papers which suggest the use of Botulinum toxin A (BTA) - otherwise known as botox - to treat depression — Magid, et al. (2015a) and ...
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Is a person who believe that their depression is curable more likely to overcome it?

According to the idea of the growth mindset a person is more likely to successfully change, when they believe that change is possible. To what extend does that apply to depression? Is a person who ...
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Probiotics and Mental Health

While trying to find research articles within the realm of Psychosynthesis, I have been looking at the "collective unconscious" Image Source: Wikipedia Commons - (CC BY-SA 3.0) Lower Unconscious ...
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Lowering people's serotonin levels does not change their mood?

I'm starting to pick off sub-topics from this omnibus question, which I think it's too broad to answer properly/directly in the SE format. So, let's start with one of the claims there: Lowering ...
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161 views

Relation of serotonin level and mood/depression

Not a biologist. Not even related to science, however I read a lot of popular psychology stuff, plus read some info about antidepressants and a question tortures me :) Antidepressants arise amount of ...
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Negative thoughts as cause or consequence of depression

Simplypsychology.org page on Cognitive Behavioral Therapy mentions that Lewinsohn (1981) studied a group of participants before any of them became depressed, and found that those who later became ...
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Evidence for existential depression as a distinct subtype?

Obviously the DSM doesn't see it as such, but the idea of Irvin D. Yalom appears to have some traction at least in magazines: Irving Yalom, in 1981, wrote about near necessity of an existential ...
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Assessments of depression: Does the rate of false positives vary between the qualification of those testing?

A friend recently asked me an interesting question to which I couldn't find the answer. Does the accuracy of depression assessments vary by the profession i.e. Nurse, GP Vs Clinical Psychologist, ...
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Which is the most valid/validated scale for diagnosis of Major depression for an Indian population?

I am planning a study of an online intervention for depression in India. We were planning to use Patient Health Questionnaire-9 (PHQ-9) for assessing the depression symptom severity. One of our ...
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994 views

Why could too much BDNF be detrimental in terms of depression and memory?

I am interested in looking at the effects of too much BDNF and other proteins such as repressor element one silencing transcription factor (REST). Most research suggest that elevated levels are ...