I recently got to wondering whether certain eye movements or pupillary responses were correlated with disorders of consciousness (coma, VS, MCS, or even locked-in syndrome). I know that the pupillary response to a direct light-source is part of the usual coma evaluation scale, but my question deals more with resting-state oculomotor activity or stimulus-evoked responses.

An example of such research might be (for example) a paper in which changes in pupil response co-varies with conscious-state changes in an MCS patient.

Does anybody know of any such research?


1 Answer 1


I have listed several articles below for your reference:

(Search terms: "oculometry pupillometry disorders of consciousness" in Google Scholar, nothing special):

Grandchamp et al, 2014, DOI: 10.3389/fpsyg.2014.00031 - A primary research article related to consciousness (mind wandering) where the authors investigated various pupillometric responses, among other measures. Good journal.

(Search terms: "pupillometry consciousness" in Google scholar):

Laeng et al., 2012, DOI 10.1177/1745691611427305 - Nice looking review on pupillometry and consciousness that should be a good source of additional references;

Smallwood et al., 2011, DOI: 10.1371/journal.pone.0018298 - A primary research article on attention and perception in Plos One. It is open source, but not my favorite journal


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