Microdialysis is a common method to study the effects of drugs on specific mamal brains zones (mostly in rats), in order to study the it's interaction with the function of those specific areas that controls or mediates in complex behavior.
There are invertebrates who are well known for providing genetic tools to study both behaviour and pharmacology of drugs, like c. elegans and Drosophila melanogaster. The last one has been also used for attention, learning and hyperactivity study, as a model for ADHD.
While I found a couple of studies which uses microdialysis on insect brains, I couldn't reach anyone for microdialysis in Drosophila. Is it possible to do microdialysis in Drosophila? Otherwise, there are alternatives to oral administration of drugs in insects like Drosophila?
-- Edit: Thanks for your insights, I have a computer science background and its hard to me to try to talk with property about these things completely out of my comfort zone. Also, I specified the original target, Drosophila Melanogaster, since there are bigger parients like Hawaian D. heteroneura and D. cyrtoloma. where current probes could be used """without too much trouble"""