In the following EM image (1um scale), there are several synapses:
Image or HD Version
What information about the synaptic strengths can be extracted from this image?
Does vesicle count contain information? What about the cross sectional "length" of the synaptic cleft? If serial sections were used to reconstruct a 3D version of a synapse, would the surface area of the synapse reflect the strength of the synapse?