There seems to be evidence to suggest that long term psychiatric conditions have effects on grey matter in the brain and the development of certain sections of the brain.
Do antipsychotics have a protective effect on the brain against the degenerative effects of schizophrenia relapse?
I have found many academic papers both supporting and contradicting a protective effect, but finding an agreed upon consensus is difficult. I'm also looking for evidence indicating what effect a schizophrenic relapse has on the brain and the exact degenerative effects that occur.