Theoretically at least, yes, it is entirely doable.
In the central nervous system including the brain, sensation, decision and reaction form a feedback loop comprising of different types of nerves. Afferent neurons sense an input such as an external stimulus, interneurons are the connectors in the local circuit, while efferent neurons carry motor signals that activate an organ.
You are apparently referring to a motor signal when you say 'the same signal'. Assuming such a signal is generated in some way and then transmitted to the organ(s), it is thereafter a purely mechanical process where the organ responds with a movement according to the signal.
It does not matter if the signal is multiplexed over to more than one organ, or if the organ happens to be natural or artificial. All that matters is the design of the artificial organ.
That is as far as the control systems part of it is concerned. However, the overall functioning is a bit more complex -- e.g., generating the intended signal, and multiplexing it to heterogeneous external organs.