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Has any research been conducted to study how individuals may vary on personality inventories, for example, the Big Five, based on whether they are cisgender versus transgender?

Broadly, inquiry may divide into the following two domains:

  1. Within a binary gender category, for example, female, do individuals tend to score differently based on whether they were assigned female versus male sex at birth?
  2. Among men and women combined, do transgender individuals, compared to cisgender, exhibit different personality trends?

It has been suggested at times in vernacular contexts that transgender individuals have greater openness to new experience, and this notion seems to have acquired some momentum in political spheres, though evidence supporting the claim is not generally provided.

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