Reading the paper "A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory" Lisman 1989, especially figure 2, it gives the impression that in the bidirectional calmoduline regulated depression and potentiation (CarD/P) there is a significant area in between the 2 stippled regions of the upper and lower panels where if I interpret the stippled regions as "regions of change", no change should occur? Often though I encounter gradual or even more stepwise graphs like this without a plateau in between:

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Am I misinterpreting something or has other evidence been found surrounding CarD/P? Are there any particular examples of brain regions with/without or with stronger/weaker no-change plateaus?


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