When talking about triptans used for migraines such as Zolimitriptan, such drugs are selective serotonin receptor agonists.
SSRIs, as their function states, are Selective Serotonin Reuptake Inhibitors.
The British National Formulary doesn't say so, but I am wondering if triptans can affect the efficacy of SSRIs. If so, how?
From the way I understand it, triptans could help boost the efficacy of SSRIs due to the fact that
- the SSRIs are blocking ("inhibiting") reuptake of serotonin, meaning more serotonin is available to pass further messages between nearby nerve cells.
- the triptans activate serotonin receptors being that they are an agonist (a chemical that binds to a receptor and activates the receptor to produce a biological response).
Am I correct?