# How much ashwagandha to relieve depression?

I've read this article, where is the herb ashwagandha which could treat depression.

Particularly:

In one controlled 60-day study in 64 stressed adults, those who took 600 mg of high-concentration ashwagandha extract per day reported a 79% reduction in severe depression, while the placebo group reported a 10% increase

When I look at the products with ashwagandha, how do I recognize what is close to 600 mg of high-concentration?

There is usually written the percentage of withanolides.

So, how to choose the right daily amount for depression in the particular product with ashwagandha?

• From the page you linked, did you read the next sentence? "However, only one of the participants in this study had a history of depression. For this reason, the relevance of the results is unclear." Reducing depression in people that don't have depression is likely meaningless. – Bryan Krause Nov 6 at 20:23
• @BryanKrause Yes, I read it, but in the citation there is a term "severe depression". There are probably other studies. See here and youtube has videos where is mentioned ashwagandha for depression treatment as well. – xralf Nov 6 at 20:38
• The site you linked to is confused. The authors do have a scale item called "severe depression" but it's not measuring severe depression, it's a scale where scoring over a certain level can be used to detect depression. Changes on the scale below that cutoff don't necessarily mean anything at all. It would be like measuring blood pressure, seeing a drop in systolic from 120 to 118 (both normal), and then claiming you've cured high blood pressure. – Bryan Krause Nov 6 at 20:49
• @BryanKrause Here is another study . I will edit the question tommorrow yet. – xralf Nov 6 at 20:52
• @xralf - your other study you linked in comments tested on rats, not humans. Although the results indicate a possible benefit in rats, it doesn't mean there will be a benefit in humans – Chris Rogers Nov 7 at 10:54