I am asking this question because I recently observed something within myself:-

I think I used to be a Borderliner plus Bipolar. I was very sensitive, and slightest of events will either induce mania in me or will just thrash me into severe depression and low self-esteem.

But since I am taking a certain medication, I have observed that I am now not experiencing above mentioned behavior within me. I am much more resilient to criticism.

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    $\begingroup$ It depends on the reason for the low self-esteem. If the feelings are a result of depression for example, brain chemical/hormonal imbalances can play a part, but it can be nothing to do with chemicals/hormones. Another aspect to this is that medications which affect the chemicals/hormones can assist in the efficacy of therapy. $\endgroup$ Commented Jul 18, 2018 at 9:04
  • $\begingroup$ It sounds to me like this is a different (complicated) way of asking whether low self-esteem can be caused by anything else than chemical imbalances in the brain. In the remaining parts of your question you are already presuming an answer. $\endgroup$
    – Steven Jeuris
    Commented Jul 19, 2018 at 16:24
  • $\begingroup$ This is a good question which sparked a separate one linked to this at psychology.stackexchange.com/q/20253 $\endgroup$ Commented Jul 20, 2018 at 8:21

1 Answer 1


Low self-esteem can be the result of severeal things, implying depression and other mental disorders, past experiences (harassement for example). We can "fix" low self-esteem through non-drug therapy, but sometimes we can't. There is no fixed answer, it varies from person to person.

My personnal experience : I am a schizoaffective and asperger person, for me, self-esteem is something really instable because of depressive/hypomaniac phases and schizophrenic symptoms. It is not something that I can control, except with high medication.

Sources and readings :

  • $\begingroup$ Welcome to the site! This is more of a comment than an answer (something you can do once you have contributed a bit more to this site), since we expect answers to include references/citations to back up claims. Therefore, this might be turned into a comment. $\endgroup$
    – Steven Jeuris
    Commented Jul 19, 2018 at 16:21

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