Akathisia is very difficult to handle. Sometimes akathisia responds to anxiolytic drugs such as benzodiazepines, propranolol, and even red wine. Amantadine, benztropine (for Parkinsonism) might also help. Mostly these are off-label prescriptions.
Meditation, exercise, and de-stressing measures are certainly helpful on general principle, though the best way to eliminate akathisia (if it is drug-induced) is to taper down the dosage or take a different medication. Finding a medication that treats the symptoms and provides a quality of life improvement despite side-effects is the job of the physician. You can think of it as quality of life improvement from reduction of symptoms plus quality of life improvement from minimization of side-effects, of which akathisia is one of the most common and unpleasant.
https://www.mdedge.com/psychiatry/article/89620/somatic-disorders/akathisia-restlessness-primary-condition-or-adverse-drug
King DJ, Burke M, Lucas RA. Antipsychotic drug-induced dysphoria. Br J Psychiatry 1995; 167:480–482.
Healy D, Farquhar G. Immediate effects of droperidol. Hum Psychopharm 1998; 13:113–120.
Jones-Edwards G. An eye-opener. OpenMind 1998; September:12,13,19.
Jones-Edwards G. On the receiving end. New Therapist 2000; 7:40–43.
Belmaker RH, Wald D. Haloperidol in normals. Br J Psychiatry 1977; 131:222–223.
Kendler KS. A medical student’s experience with akathisia. Am J Psychiatry 1976; 133:454.
Healy D, Savage M (1998) Reserpine exhumed. Brit J Psychiatry 172: 376–378.
Is it even good to work with mind under these chemicals?
are you asking whether one should undertake tasks requiring concentration, or whether it's harmful in some way? $\endgroup$ – Chuck Sherrington Dec 7 '12 at 22:37