Based on clinical data collected using different brain imaging, researchers build a mathematical model of the activity of the human brain like the hemodynamic model (Friston, 2000) that describes the changes in blood flow and blood oxygenation during brain function.
Why do we need to build and calibrate models and what is the main impact and significance of constructing and identification of the models that describe the human brain function in neuroscience field?
Friston, K.J., Mechelli, A., Price, C.J., & Turner, R. (2000). Nonlinear responses in fMRI: the Balloon model, Volterra kernels, and other hemodynamics. NeuroImage, 12(4), 466—77.
DOI: 10.1006/nimg.2000.0630 PMID: 10988040