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It seems intuitive to me that there is some kind of stress when one is put in an unfamiliar place (There's probably effect on cognitive abilities too). However, I can't find any paper in psychology which discusses that potential relationship.

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  • $\begingroup$ How would you measure the familiarity of an environment? $\endgroup$ – Seanny123 Jan 29 '18 at 2:20
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I have found the following

Older people's cardiac responses as indicators of stress in familiar and unfamiliar environments (Lewis & Phillips, 2012)

I also found:

Padilla, A. M., Alvarez, M., & Lindholm, K. J. (1986). Generational status and personality factors as predictors of stress in students. Hispanic Journal of Behavioral Sciences, 8(3), 275-288.
DOI: 10.1002/dev.420220608

stressful events center on loss of familial and cultural ties as well as on relative discomfort in an unfamiliar social environment

References

Lewis M. J. & Phillips J. E. (2012). Older people's cardiac responses as indicators of stress in familiar and unfamiliar environments. Psychophysiology, 49(4): pp. 478-483
DOI: 10.1111/j.1469-8986.2011.01321.x PMID: 22176515

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You may be interested in related research on how unfamiliar environments negatively affect sleep quality.

Tamaki, M., Bang, J. W., Watanabe, T., & Sasaki, Y. (2016). Night watch in one brain hemisphere during sleep associated with the first-night effect in humans. Current biology, 26(9), 1190-1194.

This research has also received substantial popular press coverage, for example from CNN and NPR.

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