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I've heard that cannabis exposure during teenage years increases the probability of developing schizophrenia-like symptoms later in life. What evidence is there that this is causal and not correlational?

Current references I'm reading and will try to form into an answer:

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  • $\begingroup$ A couple of things: 1) Psychotic patients make more use of cannabis than non-psychotic patients 2) people who consume cannabis between 15-18 are more likely to display psychotic symptoms at 26 3) relevant paper: ncbi.nlm.nih.gov/pmc/articles/PMC2864503 $\endgroup$ – Ebbinghaus Jun 27 '17 at 9:42
  • $\begingroup$ 1. your best bet would be twin studies (concordance rate between MZ and DZ twins with/without cannabis exposure. 2. since i last checked, there is at least one study with evidence that cannabis has anti-psychotic properties in a group of treatment refractory individuals with schizophrenia. 3. you should clarify your term "schizophrenia-like" -- do you also consider schizotypy to fit this criterion. $\endgroup$ – faustus Jul 10 '17 at 17:18

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