I know this is a silly question, but I'm curious as to what is the exact phase when we experience of the thrill of doing an exciting activity.
My understanding of feed forward systems is that the uptake of transmitter would induce the effect. Though, the simultaneous release of more dopamine is part of its effect. The synaptic gap has no mechanism of inducing a response to a transmitter besides the reuptake on the other side. I am no sort of professional so take what I say with a grain.